Pseudomonas aeruginosa maintains an inducible array of novel and diverse prophages over lengthy persistence in CF lungs

I Kyrkou, J Bartell, A Lechuga, C Lood, RL Marvig… - 2024 - researchsquare.com
… important drivers of this bacterium’s genomic plasticity [13]. … aeruginosa clinical isolates from
CF patients, such as [63, 64], … our study revealed that isolate genomes containing functional …

[HTML][HTML] Whole-genome sequence of multi-drug resistant Pseudomonas aeruginosa strains UY1PSABAL and UY1PSABAL2 isolated from human broncho-alveolar …

EL Madaha, C Mienie, HK Gonsu, RN Bughe… - PloS one, 2020 - journals.plos.org
isolates revealed nine different secondary metabolites distributed on 17 gene clusters and
15 gene … a major role in the prokaryote genomes plasticity and are generally small mobile …

[HTML][HTML] Dissemination of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa in Serbian Hospital Settings: Expansion of ST235 and ST654 Clones

J Kabic, G Fortunato, I Vaz-Moreira, D Kekic… - International Journal of …, 2023 - mdpi.com
… High adaptability, genetic plasticity, and versatile and … The geographic distribution of genomes
and the antibiotic … The bla NDM-1 was the only MBL gene detected in the present study. It …

Direct RNA nanopore sequencing of Pseudomonas aeruginosa clone C transcriptomes

MM Pust, CF Davenport, L Wiehlmann… - Journal of …, 2022 - Am Soc Microbiol
aeruginosa clone C, ie, the cystic fibrosis clinical isolate NN2 … share their core genomes and
most regions of plasticity (RGPs)… detected more differences in gene expression between the …

Diversity and evolution of an abundant ICEclc family of integrative and conjugative elements in Pseudomonas aeruginosa

V Benigno, N Carraro, G Sarton-Lohéac… - Msphere, 2023 - Am Soc Microbiol
… in Pseudomonas aeruginosa clinical isolates. Our findings revealed co-evolution between
ICEs … segments are frequently integrated have been called “regions of genome plasticity” (15). …

[HTML][HTML] Comparison of Virulence-Factor-Encoding Genes and Genotype Distribution amongst Clinical Pseudomonas aeruginosa Strains

…, S Kruszewski, A Rutkowska, P Kanarek… - International Journal of …, 2023 - mdpi.com
… Due to its high genomic plasticity and metabolic versatility, P. … of the detected virulence
genes amongst the examined P. … [28] studied a total of 189 clinical isolates and concluded that …

Transcriptional Profiling of Pseudomonas aeruginosa Infections

JG Thöming, S Häussler - Pseudomonas aeruginosa: Biology …, 2022 - Springer
large transcriptome datasets from a variety of clinical isolates … In addition to genetic diversity,
phenotypic plasticity, which … the bi-modally expressed genes revealed groups of genetically …

Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis

JA Hammond, EA Gordon, KM Socarras… - Biochemical Society …, 2020 - portlandpress.com
clinical isolates (of each of their respective species) revealed … , the number of novel genes
identified with each additional … and Pseudomonas aeruginosa the relative size of the core …

[HTML][HTML] Carbapenem-Resistant Pseudomonas aeruginosa Strains-Distribution of the Essential Enzymatic Virulence Factors Genes

T Bogiel, M Prażyńska, J Kwiecińska-Piróg, A Mikucka… - Antibiotics, 2020 - mdpi.com
aeruginosa’s genome plasticity was recently confirmed by … virulence genes detected in the
present research, also revealedclinical isolates of imipenem- and meropenem-resistant P. …

[HTML][HTML] Genomic characterization of mobile genetic elements associated with carbapenem resistance of Acinetobacter baumannii from India

…, JJ Jacob, K Vasudevan, P Mathur, P Ray… - Frontiers in …, 2022 - frontiersin.org
… the prevalent genomic features of clinical isolates of CRAb in … Escherichia coli (ATCC 25922)
and Pseudomonas aeruginosa (… Genomic analysis of AbaRs in this study unveiled novel