Modeling extracellular matrix-cell interactions in lung repair and chronic disease
TL Hackett, ET Osei - Cells, 2021 - mdpi.com
… of chronic lung diseases such as COPD, lung cancer and IPF, … In summary, ECM remodeling
in COPD affects both … of ECM components directly, or the production of ECM remodeling …
in COPD affects both … of ECM components directly, or the production of ECM remodeling …
Therapeutic targets in lung tissue remodelling and fibrosis
… pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF)… Abnormal deposition of
extracellular matrix (ECM) proteins is … remodelling that results in symptoms and impaired lung …
extracellular matrix (ECM) proteins is … remodelling that results in symptoms and impaired lung …
Interplay between extracellular matrix and neutrophils in diseases
Y Zhu, Y Huang, Q Ji, S Fu, J Gu, N Tai… - Journal of immunology …, 2021 - Wiley Online Library
… ECM remodeling by providing specific matrix-remodeling … components are associated with
the course of many chronic inflammatory diseases, especially several chronic lung diseases, …
the course of many chronic inflammatory diseases, especially several chronic lung diseases, …
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease
MM Joglekar, NJ Bekker… - … -Lung Cellular and …, 2023 - journals.physiology.org
… Extracellular matrix (ECM) remodeling has been implicated in … in chronic obstructive pulmonary
disease (COPD). Studies 38 … the component scores for each component between COPD …
disease (COPD). Studies 38 … the component scores for each component between COPD …
Granzyme B in inflammatory diseases: apoptosis, inflammation, extracellular matrix remodeling, epithelial-to-mesenchymal transition and fibrosis
F Velotti, I Barchetta, FA Cimini… - Frontiers in immunology, 2020 - frontiersin.org
… of cleaving extracellular matrix (ECM) components, … - has been reported in inflammatory
pulmonary diseases, including age-related diseases, as COPD (23, 38), and acute severe lung …
pulmonary diseases, including age-related diseases, as COPD (23, 38), and acute severe lung …
Extracellular matrix-derived peptides in tissue remodeling and fibrosis
LE de Castro Brás, NG Frangogiannis - Matrix biology, 2020 - Elsevier
… The extracellular matrix (ECM) is the non-cellular component … PGP levels were reported
to directly correlate with disease … of lung conditions, including chronic obstructive pulmonary …
to directly correlate with disease … of lung conditions, including chronic obstructive pulmonary …
Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases
… conditions arise from aberrant matrix remodelling during … response observed in these lung
diseases; possibly by hindering re-… Caspase-1 has been identified as part of the SASP and is …
diseases; possibly by hindering re-… Caspase-1 has been identified as part of the SASP and is …
The extracellular matrix and mechanotransduction in pulmonary fibrosis
… problems and in some diseases, death. It includes several lung disorders with idiopathic
pulmonary … stage fibrotic remodelling, but that ECM components also drive disease progression. …
pulmonary … stage fibrotic remodelling, but that ECM components also drive disease progression. …
Fibroblasts: The arbiters of extracellular matrix remodeling
… a wide range of disease. We highlight here fibroblast roles in the cancer, lung, and heart as
… specific ECM components such as fibrinogen which is elevated in lung fibrosis compared to …
… specific ECM components such as fibrinogen which is elevated in lung fibrosis compared to …
Link between increased cellular senescence and extracellular matrix changes in COPD
RR Woldhuis, M de Vries, W Timens… - … -Lung Cellular and …, 2020 - journals.physiology.org
… Chronic obstructive pulmonary disease (COPD) is … , part of these effects was more pronounced
in SEO-COPD. With … peripheral lung and contribute to lung tissue remodeling and small …
in SEO-COPD. With … peripheral lung and contribute to lung tissue remodeling and small …