A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
… affected by certain matrix components. Structural alterations … and remodeling and in the
regulation of cellular processes [[1, … it has been recently discovered that severe acute respiratory

Extracellular matrix remodeling in chronic liver disease

C Ortiz, R Schierwagen, L Schaefer, S Klein… - Current tissue …, 2021 - Springer
remodeling process of the extracellular matrix varies, resulting in the excessive accumulation
of its components… cells, causing the severe respiratory disease Coronavirus disease 2019 (…

Human lung extracellular matrix hydrogels resemble the stiffness and viscoelasticity of native lung tissue

RHJ de Hilster, PK Sharma… - … -Lung Cellular and …, 2020 - journals.physiology.org
lung diseases, such as COPD and idiopathic pulmonary … by extensive changes in the
extracellular matrix (ECM), the three-… tissues contained total cellular and extracellular components, …

Role of collagen in airway mechanics

L Liu, B Stephens, M Bergman, A May, T Chiang - Bioengineering, 2021 - mdpi.com
is the most abundant airway extracellular matrix component … alteration in airway diseases
and its resultant effect on airway … In airway diseases, abnormal tissue remodeling is associated …

Role of matrix metalloproteinases in angiogenesis and its implications in asthma

K Bajbouj, RK Ramakrishnan… - Journal of Immunology …, 2021 - Wiley Online Library
… Asthma is a chronic airway disorder associated with aberrant … basement membrane and
extracellular matrix remodeling to the … of ICS affect certain components of remodeling, increased …

Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments

Z Yuan, Y Li, S Zhang, X Wang, H Dou, X Yu, Z Zhang… - Molecular cancer, 2023 - Springer
… Increasing evidence suggests that the extracellular matrix (ECM) plays … components,
degradation enzymes and stiffness. These variations are under the control of cellular components in …

Airway remodeling in asthma

KP Hough, ML Curtiss, TJ Blain, RM Liu, J Trevor… - Frontiers in …, 2020 - frontiersin.org
… of matrix metalloproteinases that alter the extracellular matrix … target the ASM component of
airway remodeling. Bronchial … has been proposed to contribute to pediatric airway disease in …

Functional role of glycosaminoglycans in decellularized lung extracellular matrix

FE Uhl, F Zhang, RA Pouliot, JJ Uriarte, SR Enes… - Acta biomaterialia, 2020 - Elsevier
pulmonary disease, COPD) or idiopathic pulmonary fibrosis (IPF), will provide further insights
in disease … a major part of HS present in native tissue. No significant qualitative differences …

Vascular extracellular matrix remodeling and hypertension

Z Cai, Z Gong, Z Li, L Li, W Kong - Antioxidants & Redox Signaling, 2021 - liebertpub.com
… In this review, we hypothesize that ECM remodeling in the component profiles, mechanical
properties, degradation processes, and degraded fragment production leads to subsequent …

Extracellular matrix dynamics in vascular remodeling

Z Ma, C Mao, Y Jia, Y Fu… - American Journal of …, 2020 - journals.physiology.org
extracellular matrix (ECM), which is produced by proximal cells or tissues, is the major
component … TSP-1 deficiency causes abnormal heart, liver, and lung morphology and significantly …