Inflammation, extracellular matrix remodeling, and proteostasis in tumor microenvironment

M Marozzi, A Parnigoni, A Negri, M Viola… - International journal of …, 2021 - mdpi.com
… Altered ECM components, derived from remodeling … to present the role of different aspects
of ECM components in the … models of non-small cell lung cancer and promotes EMT in vitro …

Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine

CA Brandsma, M Van den Berge… - The Journal of …, 2020 - Wiley Online Library
lung 66, 67 are, however, indicative of lung remodeling. It has been proposed that the aged
lung is … These effects were prevented by ovariectomy and in part also by tamoxifen treatment, …

Concepts of extracellular matrix remodelling in tumour progression and metastasis

J Winkler, A Abisoye-Ogunniyan, KJ Metcalf… - Nature …, 2020 - nature.com
… of different remodelling mechanisms that can be divided into … and composition of ECM
components, thereby affecting … that may have diagnostic implications as it was shown for lung, …

Matrix metalloproteinases and their inhibitors in pulmonary fibrosis: EMMPRIN/CD147 comes into play

L Chuliá-Peris, C Carreres-Rey, M Gabasa… - International journal of …, 2022 - mdpi.com
Extracellular matrix components such as type IV collagen, … inflammatory diseases such as
acute or chronic lung diseases. … and remodeling of the extracellular matrix producing PF [297]…

The extracellular matrix and the immune system: A mutually dependent relationship

TE Sutherland, DP Dyer, JE Allen - Science, 2023 - science.org
… Shown is an overview of a healthy lung airway and the … growth factors have been shown to
bind to and remodel GAGs, … cross-talk between matrix components and the immune system. …

The ECM path of senescence in aging: components and modifiers

N Levi, N Papismadov, I Solomonov, I Sagi… - The FEBS …, 2020 - Wiley Online Library
… The extracellular matrix (ECM) is a key noncellular component … ECM components expression
and in ECM remodeling enzymes … during chronic obstructive pulmonary disease (COPD). …

Basic components of connective tissues and extracellular matrix: fibronectin, fibrinogen, laminin, elastin, fibrillins, fibulins, matrilins, tenascins and thrombospondins

J Halper - Progress in heritable soft connective tissue diseases, 2021 - Springer
… It plays a role in vascular wall remodeling and has been found in atherosclerotic plaques as
… The level of fibulin-5 is particularly high in the cardiovascular system and lung, though fibulin…

Regeneration capability of neonatal lung-derived decellularized extracellular matrix in an emphysema model

K Devi, MS Tomar, M Barsain, A Shrivastava… - Journal of Controlled …, 2024 - Elsevier
pulmonary disease (COPD) is a progressive disease that is … Decellularized extracellular
matrix (dECM) scaffolds, which … after removing immunogenic cellular components using freeze/…

Versican—a critical extracellular matrix regulator of immunity and inflammation

TN Wight, I Kang, SP Evanko, IA Harten… - Frontiers in …, 2020 - frontiersin.org
… We have been interested in versican, which is a chondroitin … of the hyalectin family of ECM
components (24), as one of the … different diseases, such as cardiovascular and lung disease, …

[HTML][HTML] Extracellular matrix-cell interactions: Focus on therapeutic applications

A Sainio, H Järveläinen - Cellular signalling, 2020 - Elsevier
… process influencing cell-signaling pathways on its part. The … Thereafter, we will discuss
the remodeling process of the ECM. … such as in interstitial lung diseases and cancer [77]. HA …