Immunomodulatory role of the extracellular matrix within the liver disease microenvironment

CE McQuitty, R Williams, S Chokshi… - Frontiers in …, 2020 - frontiersin.org
… to ECM remodeling and turnover in homeostasis and disease. … components have been
briefly studied in the liver but have … processes as well as diseases including pulmonary, renal, …

The extracellular matrix in skin inflammation and infection

K Pfisterer, LE Shaw, D Symmank… - Frontiers in cell and …, 2021 - frontiersin.org
… of ECM components (Table 1) and remodeling. … sublethal disease outcome (Gralinski et al.,
2013). SARS patients suffered severe lung injury and the urokinase pathway proved to be an …

Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study

SL Murphy, NR Balzer, T Ranheim, EL Sagen… - Frontiers in …, 2024 - frontiersin.org
… between ECM remodelling in severe COVID-19-related pulmonary disease and the …
revealed that enzymatic degradation of glycocalyx components within the ECM can uncover …

Immunologic and non-immunologic mechanisms leading to airway remodeling in asthma

L Fang, Q Sun, M Roth - International journal of molecular sciences, 2020 - mdpi.com
lung diseases later in life [90]. The mechanism by which PM2.5 activates tissue … extracellular
matrix remodeling, which were inherited to the next generations [106]. Asthma and allergic …

The role of matrix metalloproteinase in inflammation with a focus on infectious diseases

HS Lee, WJ Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
Matrix metalloproteinases (MMPs) are zinc-dependent … and remodeling of extracellular matrix
(ECM) components, such as … pulmonary disease (COPD), and coronary heart disease such …

Extracellular matrix remodeling and development of cancer

K Girigoswami, D Saini, A Girigoswami - Stem cell reviews and reports, 2021 - Springer
… growth of cells remodels the extracellular matrix (ECM). The ECM … about the components
and functions of ECM and how does it differ … , especially for lung and cardiac development [15]. …

Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update

M Mehta, DS Dhanjal, KR Paudel, B Singh… - …, 2020 - Springer
… to play an important role in the pathophysiology of respiratory diseases. These pathways, in
… clinical outcomes in respiratory diseases. A range of signaling components such as Notch, …

Airway basal cells, protectors of epithelial walls in health and respiratory diseases

E Ruysseveldt, K Martens, B Steelant - Frontiers in Allergy, 2021 - frontiersin.org
… cytoskeletal rearrangements, deposition of extracellular matrix components) to provide a rapid
… the extracellular matrix (ECM), a process referred to as ECM remodeling. The degradation …

When things go wrong: exploring possible mechanisms driving the progressive fibrosis phenotype in interstitial lung diseases

M Selman, A Pardo - European Respiratory Journal, 2021 - Eur Respiratory Soc
extracellular matrix proteins and lung remodelling. From pulmonary fibrosis to progressive
pulmonary … to release large amounts of ECM components such as collagens and fibronectin, …

Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis

S Mahalanobish, S Saha, S Dutta, PC Sil - Pharmacological Research, 2020 - Elsevier
… severe architectural remodeling in lung microenvironment of … seeds, then the extracellular
matrix (ECM) would be the soil. … affinity for extracellular matrix components, including type IV …