[HTML][HTML] Fibroageing: An ageing pathological feature driven by dysregulated extracellular matrix-cell mechanobiology
… remodelling. The scarring process characterized by excessive production and chaotic
accumulation of extracellular matrix (ECM) components… Moreover, in other interstitial lung diseases…
accumulation of extracellular matrix (ECM) components… Moreover, in other interstitial lung diseases…
Lung fibrosis and fibrosis in the lungs: is it all about myofibroblasts?
E Ortiz-Zapater, J Signes-Costa, P Montero, I Roger - Biomedicines, 2022 - mdpi.com
… extracellular matrix (ECM) components such as collagen and fibronectin … extracellular
matrix remodeling on airflow obstruction in a rat model of chronic obstructive pulmonary disease…
matrix remodeling on airflow obstruction in a rat model of chronic obstructive pulmonary disease…
Linking oxidative stress and DNA damage to changes in the expression of extracellular matrix components
SG Martins, R Zilhão, S Thorsteinsdóttir… - Frontiers in …, 2021 - frontiersin.org
… that is affected by oxidative stress and DNA damage is extracellular matrix (ECM) remodeling,
which is … The crosstalk between oxidative stress/DNA damage and ECM remodeling is not …
which is … The crosstalk between oxidative stress/DNA damage and ECM remodeling is not …
Exuberant fibroblast activity compromises lung function via ADAMTS4
… states, which we term extracellular matrix (ECM)-synthesizing, … Therapeutic targets include
components of the lung ECM, … lung injury, ECM proteases are upregulated and remodel the …
components of the lung ECM, … lung injury, ECM proteases are upregulated and remodel the …
The roles of matrix metalloproteinases and their inhibitors in human diseases
GA Cabral-Pacheco, I Garza-Veloz… - International journal of …, 2020 - mdpi.com
… that have the capacity to degrade almost every component of … coordination of extracellular
matrix remodeling with epithelial … a group of progressive lung diseases, most commonly …
matrix remodeling with epithelial … a group of progressive lung diseases, most commonly …
Emerging roles of ECM remodeling processes in cancer
… breast, lung, and ovarian tissue, there is enhanced secretion … interaction between extracellular
matrix components and host … this review, it is clear that extracellular matrix is the medium …
matrix components and host … this review, it is clear that extracellular matrix is the medium …
Extracellular vesicles: novel communicators in lung diseases
… We also explore the role EVs can potentially serve as therapeutics for these lung diseases
when … the extracellular matrix proteins of the alveoli leading to the development of COPD like …
when … the extracellular matrix proteins of the alveoli leading to the development of COPD like …
The leading role of epithelial cells in the pathogenesis of idiopathic pulmonary fibrosis
… progressive fibrotic lung disorders) have been focused on … to the abnormal extracellular
matrix remodeling. Interestingly, … key components of the hedgehog pathway in lung fibroblasts …
matrix remodeling. Interestingly, … key components of the hedgehog pathway in lung fibroblasts …
Progress in the Study of Fra-2 in Respiratory Diseases
S Zheng, Y Liu - International Journal of Molecular Sciences, 2024 - mdpi.com
… extracellular matrix [10]. Moreover, Fra-2 Tg mice exhibited significant vascular remodeling
in their pulmonary … Additionally, research has indicated that Fra-2 plays a significant part in …
in their pulmonary … Additionally, research has indicated that Fra-2 plays a significant part in …
Mesenchymal stromal cell-derived extracellular vesicles in lung diseases: current status and perspectives
SC Abreu, M Lopes-Pacheco, DJ Weiss… - Frontiers in Cell and …, 2021 - frontiersin.org
… This growth factor has the ability to stimulate deposition of extracellular matrix components
by … inflammation and remodeling in several animal models and holds therapeutic promise for …
by … inflammation and remodeling in several animal models and holds therapeutic promise for …