The interplay between systemic inflammation, oxidative stress, and tissue remodeling in tuberculosis

EP Amaral, CL Vinhaes… - Antioxidants & redox …, 2021 - liebertpub.com
… immune components that may influence the exacerbation of cellular stress … enzymes such
as the extracellular matrix (ECM) … have associated oxidative stress with various lung diseases, …

T cells promote metastasis by regulating extracellular matrix remodeling following chemotherapy

J Haj-Shomaly, A Vorontsova, T Barenholz-Cohen… - Cancer research, 2022 - AACR
pulmonary ECM remodeling functionally affects the adhesion of cancer cells to the lungs, in
part … These adhesion activities may involve integrins such as β1, which has been previously …

[HTML][HTML] Regeneration or repair? The role of alveolar epithelial cells in the pathogenesis of idiopathic pulmonary fibrosis (IPF)

P Confalonieri, MC Volpe, J Jacob, S Maiocchi… - Cells, 2022 - mdpi.com
… , such as invasion, migration, and secretion of extracellular matrix components [27]. EMT …
pathological lung remodeling, including all age-related lung pathologies and lung diseases

Elastases and elastokines: elastin degradation and its significance in health and disease

A Heinz - Critical reviews in biochemistry and molecular biology, 2020 - Taylor & Francis
… Elastin is an important protein of the extracellular matrix of … stretch-dependent remodeling
processes in the postnatal lung, in … , emphysema and chronic obstructive pulmonary disease. …

Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis

XX Nguyen, T Nishimoto, T Takihara… - … -Lung Cellular and …, 2021 - journals.physiology.org
is a pathological process characterized by fibroblast activation and proliferation and excess
deposition of extracellular matrix (ECM) components … function and is recognized to be one of …

The extracellular matrix in development

DAC Walma, KM Yamada - Development, 2020 - journals.biologists.com
… As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides
both … , after the peripodial layer is removed, ECM remodeling is responsible for initiating wing …

Autophagy, tissue repair, and fibrosis: a delicate balance

F Migneault, MJ Hébert - Matrix biology, 2021 - Elsevier
… that synthesize extracellular matrix (ECM) components and favor tissue remodeling to …
S473-Akt has been seen in IPF lung, suggesting a potential role for MTORC2 in this fibrotic …

[HTML][HTML] The charming world of the extracellular matrix: a dynamic and protective network of the intestinal wall

S Pompili, G Latella, E Gaudio, R Sferra… - Frontiers in …, 2021 - frontiersin.org
… Integrin α7β1 (binding laminins α1β1γ1 and α2β1γ1) is identified in the upper part of the crypt
Extracellular matrix remodeling: the common denominator in connective tissue diseases. …

Pulmonary fibrosis from molecular mechanisms to therapeutic interventions: lessons from post-COVID-19 patients

C Giacomelli, R Piccarducci, L Marchetti… - Biochemical …, 2021 - Elsevier
… deposition of extracellular matrix components including collagen. Interstitial lung diseases
(… small muscle (ASM) cell proliferation and airway remodelling [63]. Several other receptors …

Versican: a dynamic regulator of the extracellular matrix

S Islam, H Watanabe - Journal of Histochemistry & …, 2020 - journals.sagepub.com
… The ECM consists of fibrous and non-fibrous components. … when tissue formation or remodeling
occurs rapidly during … , it is rehashed and accumulates in many lung diseases. Vcan and …