Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis
… shown to play a key role in IPF-associated tissue remodeling. Moreover, molecules, such as
… other lung diseases, cigarette smoking has a strong association with IPF. This association is …
… other lung diseases, cigarette smoking has a strong association with IPF. This association is …
Biologics and airway remodeling in severe asthma
… Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in
part can … Increased deposition of extracellular matrix (ECM) proteins in the reticular basement …
part can … Increased deposition of extracellular matrix (ECM) proteins in the reticular basement …
Molecular pathogenesis of pulmonary fibrosis, with focus on pathways related to TGF-β and the ubiquitin-proteasome pathway
N Inui, S Sakai, M Kitagawa - International journal of molecular sciences, 2021 - mdpi.com
… extracellular matrix accumulation result in pulmonary fibrosis. … lung disease (ILD) is a diverse
group of respiratory diseases … to further development of pulmonary remodeling and fibrosis …
group of respiratory diseases … to further development of pulmonary remodeling and fibrosis …
Dermal extracellular matrix molecules in skin development, homeostasis, wound regeneration and diseases
J Huang, S Heng, W Zhang, Y Liu, T Xia, C Ji… - Seminars in Cell & …, 2022 - Elsevier
… extracellular matrix (ECM) is a dynamic structure that surrounds and anchors cellular components
… The final remodeling stage, in which the granulation tissue is remodeled in to normal …
… The final remodeling stage, in which the granulation tissue is remodeled in to normal …
Key matrix remodeling enzymes: functions and targeting in cancer
… of major components in the extracellular matrices (ECMs) under normal conditions aiming …
MT1-MMP have been shown to be upregulated in lymph nodes or lung tissues distant from the …
MT1-MMP have been shown to be upregulated in lymph nodes or lung tissues distant from the …
Airway-on-a-chip: designs and applications for lung repair and disease
TJ Bennet, A Randhawa, J Hua, KC Cheung - Cells, 2021 - mdpi.com
… relevant models for respiratory conditions will be essential for … The composition and structure
of the lung extracellular matrix … airway remodeling is a marker of many respiratory diseases, …
of the lung extracellular matrix … airway remodeling is a marker of many respiratory diseases, …
Collagen VI as a driver and disease biomarker in human fibrosis
L Williams, T Layton, N Yang, M Feldmann… - The FEBS …, 2022 - Wiley Online Library
… collagen VI, which is present in the extracellular matrix (ECM) … proposed as an indicator of
early architectural remodelling in … lung tissue (ILD), chronic obstructive pulmonary disease (…
early architectural remodelling in … lung tissue (ILD), chronic obstructive pulmonary disease (…
The role of the extracellular matrix (ECM) in wound healing: a review
RB Diller, AJ Tabor - Biomimetics, 2022 - mdpi.com
… tissue remodeling. Throughout the granulation tissue stage, matrix formation and remodeling
… The extracellular matrix (ECM) is a critical structural component of any tissue, including the …
… The extracellular matrix (ECM) is a critical structural component of any tissue, including the …
Molecular mechanisms and cellular contribution from lung fibrosis to lung cancer development
AV Samarelli, V Masciale, B Aramini, GP Coló… - International journal of …, 2021 - mdpi.com
… Interstitial lung diseases represent a broad spectrum of lung … to perceive the extracellular
matrix rigidity is due the expression … Actin cytoskeletal remodelling plays a fundamental role in …
matrix rigidity is due the expression … Actin cytoskeletal remodelling plays a fundamental role in …
MMPs as potential molecular target in epithelial-to-mesenchymal transition driven COPD progression
… Chronic obstructive pulmonary disease (COPD) is the third … in orchestrating airway remodeling,
fostering airway fibrosis, … degrading specific extracellular matrix (ECM) components and …
fostering airway fibrosis, … degrading specific extracellular matrix (ECM) components and …