… (CAS), revealed the first causative gene; FOXP2. A long hiatus then followed for CAS … or
isolated speech or language disorder [13,14,15]. The next most promising candidate gene for …

… interfere with language development to putative underlying neurobiological mechanisms of
language … or interventions that can help children to optimally develop their language skills. …

… promise for furthering our understanding of FOXP2 functions, particularly in light of links to
speech and language… drives neuronal differentiation by interacting with retinoic acid signaling …

… This includes vitamin A's involvement in higher-order cognitive functions and speech/language
disorders evident in people with FOXP2 mutations (89, 148). In quite a different direction, …

… retinoids that are structurally similar to retinol/retinoic acid are … in this study with an assigned
direction of expression (TWAS/… like FOXP2 for which a mechanistic relationship to retinol is …

… One such member, FOXP2 has been directly associated with language acquisition. …
abnormal FOXP2 function and autism and schizophrenia. It is possible that the function of FOXP2 …

… It was encouraging that oral administration of the pan-retinoic acid receptor antagonist 1
reversibly inhibited spermatogenesis, with no detectable side effects. Given that contraception is …

… direction, with higher propensity to be closer to the pia. The early appearance of gyrus/sulcus
is temporally correlated with a localized reduction in meningeal retinoic acid … , and Foxp2. …

… with inherited language or speech disorder [143]. … -Cre;Foxp2 loxP/loxP mice with cortical
Foxp2 deletion show behavior abnormalities in social interaction [154]. In addition to FOXP2, …

… as FoxP2 (forkhead box protein P2), which is known to be involved in speech and language.
… Decreased expression levels of Foxp2 and reduced Foxp2 protein expression in the cortex …