Hypertension in high school students: genetic and environmental factors: the HYGEF study

R Bigazzi, L Zagato, C Lanzani, S Fontana… - …, 2020 - Am Heart Assoc
… with information about family history of hypertension. All … , and treatment of high blood
pressure in children and … a crucial role in the future when connected to a genetic predisposition. …

[HTML][HTML] Lifestyle score and genetic factors with hypertension and blood pressure among adults in rural China

M Niu, L Zhang, Y Wang, R Tu, X Liu… - Frontiers in Public …, 2021 - frontiersin.org
… GRS, more often had a family history of hypertension, and higher … a preventive medicine
perspective using epidemiological … Genetic risk, incident stroke, and the benefits of adhering to a …

Identification, heritability, and relation with gene expression of novel DNA methylation loci for blood pressure

Y Huang, M Ollikainen, M Muniandy, T Zhang… - …, 2020 - Am Heart Assoc
… factors as estimated by the family data of the Framingham … the relative contributions of genetic
and environmental factors to the … on blood pressure, which is warranted for future research. …

Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes

MK Georgakis, D Gill, AJS Webb, E Evangelou… - Neurology, 2020 - AAN Enterprises
Future studies encompassing larger GWAS datasets for BP might identify such variants
and might thus offer deeper insights into differential effects between different classes of …

[HTML][HTML] The impact of age on genetic risk for common diseases

X Jiang, C Holmes, G McVean - PLoS genetics, 2021 - journals.plos.org
… relative risk profiles in nine diseases, including hypertension, … from the UK Biobank, a
prospective study of 500,000 people, … interval, regardless of their future events. Second, for each …

[HTML][HTML] Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women

V Steinthorsdottir, R McGinnis, NO Williams… - Nature …, 2020 - nature.com
… established variants for blood pressure (BP) and the FTO … A familial predisposition to
preeclampsia is well documented 4,… of the potential target genes is FLT1 (Supplementary Data 1). …

Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses

ST Turner, E Boerwinkle - Stroke, 2023 - Taylor & Francis
… research that have the potential to reshape approaches to the … Both genes encode members
of the WNK family of serine-… and the subsequent events that determine the therapeutic effect. …

Genome-wide polygenic score and the risk of ischemic stroke in a prospective cohort: The Hisayama study

T Hachiya, J Hata, Y Hirakawa, D Yoshida, Y Furuta… - Stroke, 2020 - Am Heart Assoc
Blood pressure was measured 3 times using an automated sphygmomanometer … the genetic
risk groups and the risk of incident IS among subgroups of the modifiable environmental risk

Sleep patterns, genetic susceptibility, and incident cardiovascular disease: a prospective study of 385 292 UK biobank participants

M Fan, D Sun, T Zhou, Y Heianza, J Lv… - European heart …, 2020 - academic.oup.com
… ), family history of heart diseases or stroke (yes/no, in the corresponding analysis), body mass
index (BMI, continuous), hypertension (… regardless of the individuals’ genetic risk profile. …

Genomics of hypertension: the road to precision medicine

S Padmanabhan, AF Dominiczak - Nature Reviews Cardiology, 2021 - nature.com
… In this Review, we provide a broad perspective on how … Family studies have shown that the
risk of hypertension in an … Other potential targets for blood pressure management identified …