The use of immunotherapy for the treatment of both solid and hematologic malignancies is
widespread. Immune checkpoint inhibitors in particular have demonstrated considerable
promise in the treatment of melanoma, non-small-cell lung cancer and other cancers. Most
immune-related adverse events (irAEs) associated with these drugs are mild to moderate,
but serious, occasionally life-threatening, adverse events are also reported. Effective
management of irAEs requires early recognition and prompt intervention with steroids …

This journal publishes original research articles and state-of-the-art reviews on all aspects of
antimicrobial and antitumor chemotherapy. The results of experimental and clinical
investigations into the microbiological and pharmacologic properties of antibacterial,
antiviral and antitumor compounds are major topics of publication. Papers selected for the
journal offer data concerning the efficacy, toxicology, and interactions of new drugs in single
or combined applications. Studies designed to determine the pharmacokinetic and …