… It worth mentioning that due to the huge variability of Fc-fusion proteins (see Figure 1 and
Supporting Information), as their size, shape, surface charges, glycosylation level, sialylation …

… One of the more recent Fc fusion proteins in development is an ACE2-Fc fusion for the
treatment of Sars-CoV-2 infections. The spike protein on the virus binds to the ACE2 receptor on …

… proteins that enable targeted delivery of therapeutic payloads which are otherwise ineffective
when administered systemically. This review focuses on recent … See Table 1 for the target …

… for cancers and current research progress of the Fc-fusion proteins for anti-tumor therapy by
… In recent years, based on the Fc-fusion protein platform technology and research conducted …

… unbound proteins to lysosomal degradation, whereas IgG, albumin or Fc fusion proteins bound
… The field of antibody therapy is rapidly evolving, and it is likely that we will see even more …

… functions of the therapeutic proteins and potentially alter the … The current study focused on
two major groups of biologics, … contained animal data without clinical data (see Discussion). …

… development of fusion proteins and their therapeutic applications for … Albumin fusion and Fc
fusion technologies have been the … From a technical perspective, fusion proteins have better …

… /2-ECD-Fc fusion protein aflibercept are approved for use in ophthalmology. Citation185 …
12 weeks resulted in maintenance of initial vision and anatomic improvements comparable with …

… Fc-fusion proteins are bioengineered polypeptides that combine a biologically active protein
… a molecule with unique properties and therapeutic potential (Linderholm & Chamow, 2014). …

… of sequences for antibodies and Fc fusion proteins that have been … view of this parallel
and rather more comprehensive development, we do not propose to provide further updates …