Neuropeptidergic control of feeding: Focus on the galanin family of peptides

P Marcos, R Coveñas - International Journal of Molecular Sciences, 2021 - mdpi.com
… of action and physiological roles played by the GAL family of … GAL in feeding behaviour,
mainly related to fat intake [25]. … feeding behaviour: from voluntary access, natural preference/…

Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour

EG Mills, C Izzi-Engbeaya, A Abbara… - Nature Reviews …, 2021 - nature.com
… mood disorders and abnormal eating behaviours, which results … ) promotes sexual partner
preference, processes sexually … (PVN)) galanin expression is increased by a high-fat diet and/…

Neuropeptide modulation of addiction: Focus on galanin

SG Genders, KJ Scheller, E Djouma - Neuroscience & Biobehavioral …, 2020 - Elsevier
purpose of this review is to assess the role of major neuropeptides in reward-seeking behaviour,
with a focus on the galanin (… -3 KO mice reported an increased intake and preference for …

Time-restricted feeding prevents metabolic diseases through the regulation of galanin/GALR1 expression in the hypothalamus of mice

J Sun, Y She, P Fang, X Gu, Z Zhang - Eating and Weight Disorders …, 2022 - Springer
… studies suggest a critical role of hypothalamic galanin and its … we subjected mice to either
ad lib or TRF of a high-fat diet for 8 … feeding to 8 h of a rodent’s preferred nocturnal feeding time …

Blunted leptin sensitivity during hedonic overeating can be reinstated by activating galanin 2 receptors (Gal2R) in the lateral hypothalamus

E Leidmaa, M Gazea, AV Patchev, A Pissioti… - Acta …, 2020 - Wiley Online Library
… of the neurocircuitry that regulates feeding behaviour.35-37 It … 40 and that ghrelin increases
the reward salience of high-fat … In support of the latter view, we found that access to hedonic …

An assembly of galaningalanin receptor signaling network

L Gopalakrishnan, O Chatterjee, C Raj… - Journal of Cell …, 2021 - Springer
Galanin has a role in mediating food intake, memory, sexual behavior, nociception and is
also … Thus, galanin acts in increasing the preference for a high-fat diet by activating feeding

[HTML][HTML] Spexin and galanin in metabolic functions and social behaviors with a focus on non-mammalian vertebrates

I Mohd Zahir, S Ogawa, NA Dominic, T Soga… - Frontiers in …, 2022 - frontiersin.org
… This review describes evidence supporting the central roles of … stimulates a preference for
a high-fat diet while increasing … Restricted feeding increased hypothalamic GALR2 in mice

[HTML][HTML] Intranasal delivery of a methyllanthionine-stabilized galanin receptor-2-selective agonist reduces acute food intake

A Kuipers, M Balaskó, E Pétervári, A Koller… - …, 2021 - Elsevier
… and/or metabolism to acute changes in dietary fat [16, 17]. … , with a more than 375-fold
preference for GAL 2 R compared to … As galanin peptides have been shown to modulate feeding, …

The Pivotal Role of Neuropeptide Crosstalk from Ventromedial-PACAP to Dorsomedial-Galanin in the Appetite Regulation in the Mouse Hypothalamus

Y Kambe, TT Nguyen, T Yasaka, TT Nguyen… - Molecular …, 2023 - Springer
fat diet feeding increased galanin expression in the PVH, and KD of galanin in the PVH
decreases the consumption of a high-fat … regions well known to control feeding behaviors (Fig. 3a…

Mouse spexin:(II) functional role as a satiety factor inhibiting food intake by regulatory actions within the hypothalamus

MKH Wong, Y Chen, M He, C Lin, Z Bian… - Frontiers in …, 2021 - frontiersin.org
… expression in omental fat is sensitive to the feeding status, the … study implies that SPX and
galanin may form an intricate … is a 29-30 aa gut-brain peptide with a strong preference for …