PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study
SB Sirima, L Richert, A Chêne, AT Konate… - The Lancet Infectious …, 2020 - thelancet.com
… this first-in-human clinical evaluation of the PRIMVAC vaccine in women in Burkina Faso
and France lays the foundation for further clinical … and PAMVAC) are currently under clinical …
and France lays the foundation for further clinical … and PAMVAC) are currently under clinical …
[HTML][HTML] Progress and insights toward an effective placental malaria vaccine
B Gamain, A Chêne, NK Viebig… - Frontiers in …, 2021 - frontiersin.org
… , and adjuvants used for the Phase I clinical trials. ClinicalTrials … clinical trials were designed
as randomized, double-blind, … The preclinical and phase I clinical trial results for PAMVAC …
as randomized, double-blind, … The preclinical and phase I clinical trial results for PAMVAC …
First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2
MJ Smit, AF Sander, MBPA Ariaans… - The Lancet …, 2023 - thelancet.com
… In this phase 1, single-centre, dose-escalation, adjuvant-selection, open-label clinical trial…
first-in-human trial of ABNCoV2. We searched PubMed on Aug 4, 2022, for clinical trials testing …
first-in-human trial of ABNCoV2. We searched PubMed on Aug 4, 2022, for clinical trials testing …
[PDF][PDF] Plasmodium falciparum Malaria Vaccines and Vaccine Adjuvants. Vaccines 2021, 9, 1072
… In addition, DCs have differential functional capabilities (tolerogenic versus inflammatory/…
in field clinical trials [190]. In a randomized, double-blind, placebo-controlled study, one …
in field clinical trials [190]. In a randomized, double-blind, placebo-controlled study, one …
Progress and new horizons toward a VAR2CSA-based placental malaria vaccine
JYA Doritchamou, J Suurbaar… - Expert Review of …, 2021 - Taylor & Francis
… fragment of VAR2CSA have entered clinical testing in humans. PAMVAC originated from the
FCR3 … in a Drosophila S2 cell system, adjuvanted with Alhydrogel® and induced adhesion-…
FCR3 … in a Drosophila S2 cell system, adjuvanted with Alhydrogel® and induced adhesion-…
Towards protective immune responses against malaria in pregnant women
CA Daubenberger - The Lancet Infectious Diseases, 2020 - thelancet.com
… First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC,
a … PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a …
a … PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a …
Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA
J Doritchamou, MA Nielsen, A Chêne, NK Viebig… - Lab Animal, 2023 - nature.com
… PMV candidates (PAMVAC, PRIMVAC and ID1-ID2a_M1010) adjuvanted with Alhydrogel,
and … First-in-human reports from clinical trials demonstrated that both PAMVAC and PRIMVAC …
and … First-in-human reports from clinical trials demonstrated that both PAMVAC and PRIMVAC …
Safety and immunogenicity of GMZ2 adjuvanted with aluminum hydroxide and CAF01 in semi-immune Gabonese volunteers and the impact of helminth infection on …
A Homoet - 2020 - ub01.uni-tuebingen.de
… Despite the promising result obtained during first in human trials, clinical development of
live … During the pre-clinical studies GMZ2 was adjuvanted with different types of adjuvants, …
live … During the pre-clinical studies GMZ2 was adjuvanted with different types of adjuvants, …
Plasmodium falciparum Malaria Vaccines and Vaccine Adjuvants
… In addition, DCs have differential functional capabilities (tolerogenic versus inflammatory/…
in field clinical trials [190]. In a randomized, double-blind, placebo-controlled study, one …
in field clinical trials [190]. In a randomized, double-blind, placebo-controlled study, one …
… full-length circumsporozoite protein-based Plasmodium falciparum vaccine is well-tolerated and highly immunogenic in phase 1 first-in-human clinical testing
DAJ Friedman-Klabanoff, AA Berry, MA Travassos… - Vaccine, 2021 - Elsevier
… 1 first-in-human dose-escalation clinical trial of full-length rCSP vaccine given with or without
GLA-LSQ adjuvant. … The two cohorts that received the placental malaria vaccine, PAMVAC, …
GLA-LSQ adjuvant. … The two cohorts that received the placental malaria vaccine, PAMVAC, …