A multidimensional approach to frailty in older people

A Pilotto, C Custodero, S Maggi, MC Polidori… - Ageing research …, 2020 - Elsevier
Frailty is an important factor determining a higher risk of adverse … frailty as a loss of physical
functions or as accumulation of multiple deficits. Recently, a novel conceptual model of frailty

Marginalized frailty-based illness-death model: application to the UK-Biobank survival data

M Gorfine, N Keret, A Ben Arie, D Zucker… - Journal of the American …, 2021 - Taylor & Francis
… -death marginalized hazards and survival functions. We … frailty model so that the marginalized
hazard functions obey a specified model, such as the Cox model, that is free of the frailty

Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?

G Bai, A Szwajda, Y Wang, X Li, H Bower… - Age and …, 2021 - academic.oup.com
… Generalised survival models were used in the survival analysis. … In this analysis, we found
that the frailty trajectories across 40 years before death differed by age at death, with all the …

Dynamic risk prediction via a joint frailty-copula model and IPD meta-analysis: Building web applications

T Emura, H Michimae, S Matsui - Entropy, 2022 - mdpi.com
… , we utilized a joint frailty-copula model describing the dependence between time to … survival
(OS) [9,10,28,29,30]. The joint frailty-copula model differs from the standard joint models for …

Bayesian survival analysis with INLA

D Alvares, J Van Niekerk, ET Krainski… - Statistics in …, 2024 - Wiley Online Library
… Inspired by “Bayesian survival analysis with BUGS”,17 this tutorial aims to implement the
same survival models presented … So, we setup an INLA survival object and fit the frailty model: …

Trajectories of frailty in aging: prospective cohort study

J Verghese, E Ayers, S Sathyan, RB Lipton, S Milman… - PLoS …, 2021 - journals.plos.org
… of frailty trajectories for mortality over established survival predictors,[25] we further adjusted
the model … This subgroup analysis in1005 individuals (120 deaths) with data available on all …

Frailty changes predict mortality in 4 longitudinal studies of aging

E Stolz, EO Hoogendijk, H Mayerl… - The Journals of …, 2021 - academic.oup.com
… The well-established cumulative deficit model (2) depicts frailty as a state of risk due to a … a
continuous frailty index (FI) ranging from 0 to 1. A recent systematic review and meta-analysis (…

High-dimensional survival analysis: Methods and applications

S Salerno, Y Li - Annual review of statistics and its application, 2023 - annualreviews.org
survival prognostication. In this article, we review various cutting-edge methods that handle
survival … innovations in machine learning approaches for survival prediction. We cover the …

Prediction of remaining useful life (RUL) of Komatsu excavator under reliability analysis in the Weibull-frailty model

A Ghomghaleh, R Khaloukakaie, M Ataei, A Barabadi… - Plos one, 2020 - journals.plos.org
… the RUL under the reliability analysis in a frailty model. The proposed … frailty model was
selected to describe the failure behavior and compare it with the classical-exponential model

Frailty in the oldest old: is the current level or the rate of change more predictive of mortality?

E Stolz, H Mayerl, EO Hoogendijk - Age and ageing, 2022 - academic.oup.com
… Compared to Cox regression models, the joint models used in our analyses allow for a
better monitoring of frailty trajectories by allowing to take non-linear within-person changes into …