Compound negative binomial multivariate correlated frailty model for long-term survivors

AD Dabade - Communications in Statistics-Simulation and …, 2024 - Taylor & Francis
… Hence, frailty distribution should provide a positive mass at zero. In this article, a new
correlated frailty model with compound negative binomial distribution as frailty distribution, is …

Frailty as a predictor of short-and long-term mortality in critically ill older medical patients

JA Silva-Obregón, M Quintana-Díaz… - Journal of critical …, 2020 - Elsevier
… hazard model was used in the multivariable analysis to determine the association between
frailty and mortality using the CFS dichotomized into frail (CFS ≥ 5) and non-frail (CFS < 5) …

[HTML][HTML] Age and life expectancy clocks based on machine learning analysis of mouse frailty

MB Schultz, AE Kane, SJ Mitchell… - Nature …, 2020 - nature.com
… Standard, rather than survival analysis-oriented, versions of these regression algorithms
were used as we have no censored data in our dataset, and we are treating our longitudinal …

Strategies for handling missing data that improve Frailty Index estimation and predictive power: lessons from the NHANES dataset

G Pridham, K Rockwood, A Rutenberg - GeroScience, 2022 - Springer
Frailty Index (FI) and survival analysis, along with several mitigation strategies. We observed
distinct block patterns of missing variables in the dataset. These blocks showed significant …

[HTML][HTML] Frailty as measured by the Risk Analysis Index is associated with long-term death after carotid endarterectomy

KA Rothenberg, EL George, N Barreto, R Chen… - Journal of vascular …, 2020 - Elsevier
… Discrimination of Cox regression models was assessed by area under the receiver … for
survival analysis. In our post hoc analysis, we created Kaplan-Meier curves to analyze patient …

A comparison of three different approaches to defining frailty in older patients with multiple myeloma

A Isaacs, M Fiala, S Tuchman, TM Wildes - Journal of geriatric oncology, 2020 - Elsevier
… We examined three different models of frailty using data available in the … frailty in our cohort:
the IMWG frailty model [16], the R-MCI [17] and the CFI [18]. In the IMWG frailty index, frailty

[HTML][HTML] Sex differences in frailty: comparisons between humans and preclinical models

AE Kane, SE Howlett - Mechanisms of Ageing and Development, 2021 - Elsevier
… This review highlights evidence for male-female differences in frailty from both the clinical
literature and in animal models of frailty. We review evidence for higher frailty levels in female …

[HTML][HTML] Impact of frailty on persistent critical illness: a population-based cohort study

JN Darvall, R Bellomo, M Bailey, PJ Young… - Intensive Care …, 2022 - Springer
analyses including only the 76 ICUs with low levels of frailty missingness. We only
incorporated severity of illness on ICU admission, and did not recalculate it on subsequent ICU …

[HTML][HTML] Frailty status among older critically ill patients with severe acute kidney injury

W Beaubien-Souligny, A Yang, G Lebovic, R Wald… - Critical Care, 2021 - Springer
… For the purpose of this analysis, patients without frailty status data recorded … frailty and
deterioration of frailty status during follow-up at 6 months and 12 months [4, 13]. New onset frailty

[HTML][HTML] Variation in center-level frailty burden and the impact of frailty on long-term survival in patients undergoing elective repair for abdominal aortic aneurysms

EL George, R Chen, AW Trickey, BS Brooke… - Journal of vascular …, 2020 - Elsevier
… In our analysis, 1-year mortality for frail patients undergoing EVAR and OAR was high (∼15%-20%).
The Endovascular Aneurysm Repair and Outcome in Patients Unfit for Open Repair …