Pivotal role of the carbohydrate recognition domain in self-interaction of CLEC4A to elicit the ITIM-mediated inhibitory function in murine conventional dendritic cells in …

J Nasu, T Uto, T Fukaya, H Takagi, T Fukui… - International …, 2020 - academic.oup.com
… for the ITIM-mediated suppressive function in conventional dendritic cells (cDCs). Human …
well as B cells. The extracellular portion of CLEC4A specifically binds to a murine cDC cell line …

Transcriptional networks driving dendritic cell differentiation and function

SL Nutt, M Chopin - Immunity, 2020 - cell.com
… Here, we review the cellular and molecular evidence that underpins current … murine and
human systems. We discuss these models in the context of the diversity revealed by single-cell

Dendritic cells revisited

M Cabeza-Cabrerizo, A Cardoso… - Annual review of …, 2021 - annualreviews.org
Dendritic cells (DCs) possess the ability to integrate information about their environment and
communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, …

Review of dendritic cells, their role in clinical immunology, and distribution in various animal species

MY Zanna, AR Yasmin, AR Omar, SS Arshad… - International journal of …, 2021 - mdpi.com
… a “dendritic cell” because of its myriad filopodial protrusions that extended from the cell body.
… similar immunophenotype and functions to their human and murine pDC counterparts [51]. …

Kidney dendritic cells: fundamental biology and functional roles in health and disease

C Kurts, F Ginhoux, U Panzer - Nature Reviews Nephrology, 2020 - nature.com
Dendritic cells (DCs) are chief inducers of adaptive immunity and regulate local
inflammatory responses across the body. Together with macrophages, the other main type of …

[PDF][PDF] Dendritic cells as key players in systemic lupus erythematosus

C Kaewraemruaen, P Ritprajak… - Asian Pacific Journal of …, 2020 - apjai-journal.org
… Human cDC1s are characterized by CD141 (blood dendritic cells antigen (BDCA) 3)
expression, while cDC2s are restricted to CD1c (BDCA1) expression.Human and murine cDCs …

Dendritic cells and their role in immunotherapy

A Gardner, Á de Mingo Pulido, B Ruffell - Frontiers in immunology, 2020 - frontiersin.org
… specific dendritic cell subsets in regulating the anti-tumor immune response, as well as the
current status of dendritic cell… Extracting murine cDCs from tumors allows them to activate and …

A conserved dendritic-cell regulatory program limits antitumour immunity

B Maier, AM Leader, ST Chen, N Tung, C Chang… - Nature, 2020 - nature.com
functions of these cells may be altered in some lesions. Here, using single-cell RNA sequencing
in human and mouse non-small-cell lung cancers, we identify a cluster of dendritic cells

Dendritic cell regulation of T helper cells

X Yin, S Chen, SC Eisenbarth - Annual review of immunology, 2021 - annualreviews.org
… As the professional antigen-presenting cells of the immune system, dendritic cells (DCs) …
Another study identified murine and human DCs with features of both pDCs and cDC2s; the …

[HTML][HTML] Inflammasomes within hyperactive murine dendritic cells stimulate long-lived T cell-mediated anti-tumor immunity

D Zhivaki, F Borriello, OA Chow, B Doran, I Fleming… - Cell reports, 2020 - cell.com
… Central to anti-tumor immunity are dendritic cells (DCs), which stimulate long-lived protective
T cell … to infection and cancer are dendritic cells (DCs), which patrol the tissues of the body ( …