Alterations in brain synaptic proteins and mRNAs in mood disorders: a systematic review and meta-analysis of postmortem brain studies

E Leung, EW Lau, A Liang, C de Dios, R Suchting… - Molecular …, 2022 - nature.com
… Given these discrepancies, our primary goal in this review and … on ketamine on synaptic
proteins [98], the evidence of ketamine … and new drug candidates-Nrf2 activators and GSK-3

Lihong Ye1, Jiayi Wu2, Zuyi Liu1, Di Deng1, Shasha Bai1, Lei Yang1, Yao Xuan1, Zehao Liu1, Yafei Shi2, Zhongqiu Liu1, Rong Zhang1* and Jinlan Zhao1

M Sowa-Kucma, A Bertollo… - … -Searching for New …, 2024 - books.google.com
… spine remodeling in regulating depressive behavior, the impact of early life … Targeting
synaptic structural plasticity within the NAc could … Ketamine, a pharmacological agent acting as a …

Dopamine dynamics and neurobiology of non-response to antipsychotics, relevance for treatment resistant schizophrenia: a systematic review and critical appraisal

F Iasevoli, C Avagliano, L D'Ambrosio, A Barone… - Biomedicines, 2023 - mdpi.com
… a model of acute and subchronic ketamine treatment in rats [215], … Moreover, GSK-3 activation
appears to be also regulated by … -2/AKT1/GSK-3 pathway may represent a major target for …

Effects of psychedelics on neurogenesis: A systematic review of pre-clinical studies

RV Lima da Cruz, RN Leao, TC Moulin - bioRxiv, 2023 - biorxiv.org
… after psychedelics interventions and aim to provide a … The other five studies explored
the effects of ketamine in … 60 (P60) showed improved performance in the forced swim test …

[PDF][PDF] The antimanic-like effects of andrographolide and quercetin

LKS Kanazawa - 2021 - cris.maastrichtuniversity.nl
… Of note, Ser9-inhibition is on a pool of free GSK-3 that is not … neurotransmission by
downregulating NMDA receptors. Lithium … The aim of the thesis was to investigate the possible …

Xiaoqiang Wang1, 2, Hongyan Zhang1, Ruiqing Zong1, Weifeng Yu2*, Feixiang Wu1* and Yiran Li1

C Duan, F Forfori, L Xie, Y Li, F Wu… - … organ dysfunctions in …, 2023 - books.google.com
… These predictors could be new biomarkers or targets for … The potential for anesthetics to
enhance cognitive performance … of the glutamate NMDA receptors by ketamine or esketamine …

[HTML][HTML] The complex role of the chemokine CX3CL1/Fractalkine in major depressive disorder: a narrative review of preclinical and clinical studies

S Bridge, SN Karagiannis, A Borsini - Brain, Behavior, & Immunity-Health, 2024 - Elsevier
… In this narrative literature review, we aim to address the absence of … action of PP results in
AMPA downregulation and LTD. … ketamine (0.5mg/kg), a psychotropic agent with established …

Recent approaches to target apoptosis in neurological disorders

RK Sodhi, AK Grewal, J Madan, TGS Jhajj… - … and Targeted Therapies …, 2021 - Elsevier
… have been used to target the precise regulator of apoptosis in … intracellular calcium entry
via NMDA receptors. Statins also … The GSK-3 is a conserved signaling molecule with essential …

The shared molecular mechanisms underlying aging of the brain, major depressive disorder, and Alzheimer's disease: The role of circadian rhythm disturbances

M Amidfar, ML Garcez, YK Kim - Progress in Neuro-Psychopharmacology …, 2023 - Elsevier
… Interestingly, ketamine and its rapid and relatively sustained … Mice with targeted disruption
of genes involved in control of mutation rate, regulation of chromosome and telomere stability, …

Modelling the Effects of β-Arrestin-Mediated Signaling in Cortical D2R Expressing Neurons Using Crispr-Cas9

MF Olufemi - 2023 - search.proquest.com
… nucleus and their involvement in hormonal regulation (Klein et al. … Dopamine afferents
target two distinct populations of … also correlate with cognitive performance in human subjects, …