… neurotransmitters, neuromodulatory regulators, or from a trigger … to NMDA receptor ratio
transiently, a marker of increased … -PSD-95, the target of GSK-3 that would promote AMPA-GluA1 …

… The aim of this study was to summarize and highlight the … is explicitly linked to the suppression
of NMDAR-mediated burst … , AMPA was found to be an essential element in mediating …

… GSK-3: a key regulatory target for ketamine's rapid antidepressant effects mediated by enhanced
AMPA to … the KET antidepressant effect goes beyond the NMDA receptor inhibition and …

… with rapid-acting antidepressant effects, eg, NMDA receptor … 4-isoxazole propionic acid
(AMPA) receptor, kainate receptor … -Akt signaling can inhabit GSK-3 activity; GSK-3 can inhibit …

… -synaptic GluN2Bcontaining NMDAR by ketamine subsequently … linked to improvement of
AMPA throughput, and followed by … GSK-3 inhibitor lithium enhances the antidepressant effects …

… administrations and cognitive performance was generally found to … GSK-3 as an important
regulatory target for ketamine’s … Although NMDA receptor inhibition and subsequent AMPA …

… In summary, ketamine is an NMDAR antagonist developed as a … Hypothetically, these
pyramidal neurons rely on AMPA … , phosphorylation of GSK-3 might be caused by the ketamine-…

… in BDNF, TrNB and GSK-3-associated pathways in TRD … Enhanced glutamate signalling via
the AMPA receptors in the … Ketamine reduces NMDA receptor-induced neurotoxicity and also …

… the structure of GSK-3, the regulation of GSK-3 activity, and its … GSK-3β regulates AMPA
receptor internalization and … of NMDA receptor-mediated signaling by ketamine evoked …

… and potential downstream targets of GSK-3 that may … Thus, in this review, increased activation
of GSK-3 coincident with … susceptibility genes, resulting in NMDAR hypofunction in SZ […