Connexin and gap junctions: perspectives from biology to nanotechnology based therapeutics

S Jindal, S Chockalingam, SS Ghosh… - Translational …, 2021 - Elsevier
… The concept of gap junctions and their role in intercellular communication has been known
… the fundamental biology of connexins in mediating gap junction intercellular communication (…

[HTML][HTML] Diversity of Intercellular Communication Modes: A Cancer Biology Perspective

T Ebrahim, AS Ebrahim, M Kandouz - Cells, 2024 - mdpi.com
… There is abundant literature that associates the different junctions to cancer. The role of gap
junctional intercellular communications (GJICs) in cancer development and progression, as …

[HTML][HTML] Gap junction-mediated cell-to-cell communication in oral development and oral diseases: a concise review of research progress

W Liu, Y Cui, J Wei, J Sun, L Zheng, J Xie - International journal of oral …, 2020 - nature.com
communication between cells may disrupt biological … sites by phosphatases in response to
a biological stressor, such as … in regulating gap junctional intercellular communication (GJIC), …

[HTML][HTML] Recent advances in connexin gap junction biology

PD Lampe, DW Laird - Faculty Reviews, 2022 - ncbi.nlm.nih.gov
… As an example, considerable evidence suggests that Cx31.3 may not even have the capacity
to form traditional gap junction intercellular channels, raising the notion that their main role …

[HTML][HTML] Gap junction-dependent and-independent functions of Connexin43 in biology

Y Zhu - Biology, 2022 - mdpi.com
… family genes; connexin genes took over the gap junction function for the first time in the … for
intercellular communication [3]. After the connexin proteins took over the gap junction function…

[HTML][HTML] Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications

MZ Totland, NL Rasmussen, LM Knudsen… - Cellular and Molecular …, 2020 - Springer
… This review provides an up-to-date overview of the current understanding of the role of
connexin ubiquitination in the regulation of gap junctional intercellular communication. We also …

Intercellular junctions and cellcell communication in the skeletal system

JP Stains, F Fontana, R Civitelli - Principles of bone biology, 2020 - Elsevier
… by cellcell interactions and intercellular communication results in context-specific biological
Cellcell adhesion molecules and gap junctions represent possible targets for therapeutic …

[HTML][HTML] Cell systems bioelectricity: how different intercellular gap junctions could regionalize a multicellular aggregate

A Riol, J Cervera, M Levin, S Mafe - Cancers, 2021 - mdpi.com
… obtain with only one type of connexin gap junction for biologically plausible single-cell and
… been further reflected in distinct intercellular communication and reduced resting membrane …

[HTML][HTML] Direct cell-cell communication via membrane pores, gap junction channels, and tunneling nanotubes: medical relevance of mitochondrial exchange

E Eugenin, E Camporesi, C Peracchia - International journal of molecular …, 2022 - mdpi.com
gap junctions are the major means of cell-cell communication, in the early 1980s, evidence
surfaced that some cells might also communicate … They proposed a novel biological means of …

[HTML][HTML] Gap junctions and connexins in cancer formation, progression, and therapy

R Ruch - Cancers, 2020 - mdpi.com
gap junctional intercellular communication (GJIC) and gap junction proteins (connexins) in
the biology, … Gap junctions are a unique form of cellular junction in that they primarily serve as …