Cost-effectiveness analysis of gefitinib plus chemotherapy versus gefitinib alone for advanced non-small-cell lung cancer with EGFR mutations in China

Y Shu, Q Zhang, X He, L Chen - Cancer Management and …, 2021 - Taylor & Francis
… The aim of this study was to evaluate the cost-effectiveness of gefitinib plus chemotherapy
(GCP) versus gefitinib alone for advanced non-small-cell lung cancer (NSCLC) patients with …

Therapeutic effect of gefitinib on patients with advanced EGFRmutation NSCLC.

A Xu, H Yan, T Bu - Pakistan Journal of Pharmaceutical …, 2021 - search.ebscohost.com
… Abstract: This study aims to study the role of gefitinib on patients with advanced … of gefitinib
combined with pericardial perfusion in the treatment of advanced non-small cell lung cancer. …

Emerging therapeutic agents for advanced non-small cell lung cancer

R Chen, R Manochakian, L James, AG Azzouqa… - Journal of hematology & …, 2020 - Springer
… clinical trials in advanced/metastatic non-small cell lung cancer. Each study was individually
reviewed and data points … Gefitinib is the first tested EGFR inhibitor in advanced NSCLC. …

Treatment Strategies for Non-Small Cell Lung Cancer with Common EGFR Mutations: A Review of the History of EGFR TKIs Approval and Emerging Data

JA Marin-Acevedo, B Pellini, EMO Kimbrough, JK Hicks… - Cancers, 2023 - mdpi.com
… Erlotinib was better tolerated, and its use was associated … (EMA) approved gefitinib for the
treatment of advanced EGFR-… evaluated the use of osimertinib after progression on gefitinib or …

Biomarker guided treatment in oncogene-driven advanced non-small cell lung cancer in older adults: a Young International Society of Geriatric Oncology Report

K Christofyllakis, AR Monteiro, O Cetin, IA Kos… - Journal of Geriatric …, 2022 - Elsevier
Gefitinib was compared to chemotherapy as first-line … EGFR mutations treated with gefitinib
had longer mPFS compared to … Older-patient specific data regarding gefitinib is available from …

Comparative efficacy and safety of first-line treatments for advanced non-small cell lung cancer with ALK-rearranged: a meta-analysis of clinical trials

H Ma, Y Liu, K Ding, Y Liu, W Zhao, Y Zhu, X Chang… - BMC cancer, 2021 - Springer
… Bayesian ranking profiles of comparable treatments on efficacy for patients with advanced
ALK-rearranged, non-small cell lung cancer. The profiles indicate the probability of each …

[HTML][HTML] Anlotinib combined with gefitinib can significantly improve the proliferation of epidermal growth factor receptor-mutant advanced non-small cell lung cancer in …

T Li, Y Qian, C Zhang, J Uchino… - … Lung Cancer …, 2021 - ncbi.nlm.nih.gov
… The research object of this paper is patients with advanced non-small cell EGFR mutation
positive. After targeted therapy, it falls between first-line therapy and second-line therapy, …

Cost-effectiveness analysis of the first‐line EGFR‐TKIs in patients with advanced EGFR-mutated non-small-cell lung cancer

J Aguilar-Serra, V Gimeno-Ballester… - Expert Review of …, 2022 - Taylor & Francis
… The comparator used in this analysis was gefitinib. Platinum-based chemotherapy was
excluded as a standard first-line therapy in our study because TKIs have shown a better …

The resistance to EGFR-TKIs in non-small cell lung cancer: from molecular mechanisms to clinical application of new therapeutic strategies

C Laface, FM Maselli, AN Santoro, ML Iaia, F Ambrogio… - Pharmaceutics, 2023 - mdpi.com
… The activation of the insulin-like growth factor 1 receptor (IGF-1R) seems to be related to
EGFR-TKI resistance as shown in in vitro studies on lung cancer cell lines resistant to gefitinib

Gefitinib increases the incidence of QT prolongation in patients with non-small cell lung cancer

G Maimaitituersun, B Abulimiti, M Jin… - International Heart …, 2023 - jstage.jst.go.jp
… treatment for lung cancer may increase the risk of prolonged QTc in patients. First, almost all
patients undergoing surgery for lung cancer in this study started to take gefitinib after surgery…