Improving molecular therapy in the kidney
JD Rubin, MA Barry - Molecular diagnosis & therapy, 2020 - Springer
… in gene delivery to the kidney and the field of gene therapy … of kidney genetics to work toward
developing gene therapy … to a rat kidney destined for kidney transplantation over the course …
developing gene therapy … to a rat kidney destined for kidney transplantation over the course …
[HTML][HTML] Gene therapy clinical trials, where do we go? An overview
… gene therapy, we reviewed current gene therapy products as well as gene therapies that may
be approved in the near future… genetic diseases, may show higher efficacy and feasibility of …
be approved in the near future… genetic diseases, may show higher efficacy and feasibility of …
The horizon of gene therapy in modern medicine: advances and challenges
B Arjmand, B Larijani, M Sheikh Hosseini… - Cell Biology and …, 2020 - Springer
… As mentioned before, therapeutic efficacy following gene therapy has now been reported
for several inherited diseases including SCID-X1, ADA-SCID, CGD, LCA, …
for several inherited diseases including SCID-X1, ADA-SCID, CGD, LCA, …
[HTML][HTML] Recent advances and clinical outcomes of kidney transplantation
… Although several studies have suggested the safe use of sodium glucose transport 2 (SGLT2)
inhibitors in kidney transplant recipients [128], future studies assessing their efficacy and …
inhibitors in kidney transplant recipients [128], future studies assessing their efficacy and …
[HTML][HTML] Complement-targeted therapies in kidney transplantation—Insights from preclinical studies
… ) to assess safety and efficacy of eculizumab as ABMR prevention following HLA-incompatible
kidney transplantation was terminated due to lack of … Future directions and conclusion …
kidney transplantation was terminated due to lack of … Future directions and conclusion …
[HTML][HTML] The future of gene therapy for transfusion-dependent beta-thalassemia: The power of the lentiviral vector for genetically modified hematopoietic stem cells
P Rattananon, U Anurathapan, K Bhukhai… - Frontiers in …, 2021 - frontiersin.org
… new era of medicine. Many researchers have attempted to develop and modify novel strategies
to improve future directions of HSC gene therapy… outcome with effectiveness are urgently …
to improve future directions of HSC gene therapy… outcome with effectiveness are urgently …
[HTML][HTML] IL-6 directed therapy in transplantation
CL Miller, JC Madsen - Current transplantation reports, 2021 - Springer
… shown efficacy in single-arm, pilot trials aimed at reducing HLA antibody in highly sensitized
patients awaiting kidney transplantation … In this study, 30 kidney transplant recipients with …
patients awaiting kidney transplantation … In this study, 30 kidney transplant recipients with …
[HTML][HTML] Gene therapy strategies for idiopathic pulmonary fibrosis: recent advances, current challenges, and future directions
… to gene therapy. We then present an evaluation of published animal studies to establish
whether gene therapy could be a feasible therapeutic … to transform gene therapy concepts into …
whether gene therapy could be a feasible therapeutic … to transform gene therapy concepts into …
Donor-derived cell-free DNA in solid-organ transplant diagnostics: indications, limitations, and future directions
A Kataria, D Kumar, G Gupta - Transplantation, 2021 - journals.lww.com
… focuses on kidney transplants, there are several recent as well as ongoing research studies
on … Finally, cost-effectiveness studies will be needed to guide the ideal incorporation of dd-…
on … Finally, cost-effectiveness studies will be needed to guide the ideal incorporation of dd-…
[HTML][HTML] Current and future directions of stem cell therapy for bladder dysfunction
JH Shin, CM Ryu, HY Yu, DM Shin… - Stem Cell Reviews and …, 2020 - Springer
… perivascular-like structure up to 30 days after transplantation [74]. These reports from the
Choo group provide the first evidence for improved therapeutic efficacy, long-term safety, and in …
Choo group provide the first evidence for improved therapeutic efficacy, long-term safety, and in …