… In a series of human renal transplant biopsies, all biopsy specimens showed P16 INK4A
staining in the nuclei of distal tubules and collecting duct but staining was also present in …

… Delayed graft function is a frequent complication of kidney transplantation that requires
dialysis in the first week posttransplant. Materials and Methods. We searched for the most …

… Future Direction … Longterm safety and efficacy of factor IX gene therapy in hemophilia B. N
Engl J Med 371: 1994–2004, … Update on the safety and efficacy of retroviral gene therapy for …

… area and explore future directions for translational research. … insights into a certain drug’s
effectiveness, although this is an invasive … a deceased-donor kidney transplant within 72 h after …

… have emerged as potential therapeutic targets. Circulating proteins that contribute to GFB
breakdown following kidney transplantation may also be targeted for therapeutic benefit. Such …

… Prospective studies reporting safety and efficacy of CD19-directed CAR-T therapy in other B
… potentially demonstrates safety and efficacy of IECT, the evidence will be critically reviewed …

… We administer this on day −3 (ie, 3 d before the kidney transplant [day 0]) to deplete circulating
T … Preliminary evidence of safety and efficacy in SLE patients, but larger sample size is …

… -line therapy fails, and taking into account increased toxicity in transplant recipients, new
therapies combining high efficacy … Although very promising new treatment options have been …

… AMR, despite the weakness of evidence in support of efficacy. In particular, their ability …
new agents and clinical trials are needed urgently. Future directions in this field will require new …

… To evaluate the longitudinal pattern of access to kidney transplantation over the past two …
or placed on a transplant waiting list from 1997 to 2016 in the United States Renal Data System. …