… Here, we investigate the genetic relationship between ALS and over 700 traits using …
correlations with ALS. We provide independent evidence for a genetic relationship between ALS …

… Amyotrophic lateral sclerosis (ALS), classically described as … explored the genetic correlation
between schizophrenia and … and significant correlation between schizophrenia and ALS. …

… a large study of amyotrophic lateral sclerosis (ALS; 29,612 … ALS genetic liability and identified
46 genetically correlated traits, … directionality of these genetic correlations, we conducted a …

… Our findings demonstrate a specific genetic correlation between ALS and autoimmune
diseases and identify shared risk loci, including three novel ALS risk genes. These results provide …

… studies have suggested comorbidities between amyotrophic lateral sclerosis (ALS) and …
their shared genetic architecture. To examine whether genetic enrichment exists between ALS …

… overlap between amyotrophic lateral sclerosis and schizophrenia.Indeed, GLT8D1, a
recently identified risk gene for amyotrophic lateral sclerosis, is also a schizo phrenia risk gene.…

… in schizophrenia risk (Table 2A). Genetic correlation between ALS and schizophrenia
risk has been previously shown, where SCFD1 was identified as a candidate gene driving …

… the genetic correlation between them and prioritized pleiotropic genes through a multiple-tissue …
(MR) analyses to evaluate the causal relationship between the 2 diseases. A mediation …

… between FTD and other neuropsychiatric conditions such as schizophrenia and ASD in
addition to genetic susceptibility, brain network disruption and co-morbidities [5, 13]. …

… Amyotrophic lateral sclerosis is a rare and fatal neurodegenerative disease characterised …
and psychiatric diseases including PD [117] and Schizophrenia [118], suggesting a wider role …