… reviews genetic modifier studies in DMD to date and discusses the effect of genetic modifiers
on … (inclusion of genotype-stratified subgroup analyses) and therapeutic approaches. The …

… muscular dystrophy (DMD) phenotype. This meta-analysis aims to estimate the association
of genetic … ) and secreted phosphoprotein 1 (SPP1) genes, among others, with age of loss of …

… of GCs treatment, which is worth further discussing considering GCs has … genetic modifier
of the long-term effect of GCs treatment in Chinese patients with Duchenne muscular dystrophy…

… genes different from DMD, that may influence the pathological consequences of dystrophin
… Here we aimed at describing the natural history of, and effect of GC treatment on respiratory …

… genetic modifiers in DMD suggests that the ‘effect size’ of the … Effect size of genetic modifiers
can be quantitated in DMD by … Genetic modifiers to date all show about 1-2 years change in …

… the effects of dystrophin variations and genetic modifiers of DMD on rate and age of muscle
… of different genetic modifiers of disease progression in DMD on muscle fatty replacement. …

… This line of inquiry raises the question: how might more effective DMD therapies be … at
genetic modifiers of dystrophin expression and how the therapeutic utilization of those modifiers is …

… muscles lack dystrophin, efficient gene therapy should allow the expression of a new dystrophin
gene not only in limb muscles but … The estimation of how much dystrophin is required to …

… DMD is an X-linked muscular dystrophy caused by mutations in the DMD gene. The disease
begins in childhood and the most common characteristics include calf pseudohypertrophy, …

… Here, we aimed to verify if genetic modifiers of LoA in DMD, both cis- and trans-acting,
also affect the performance of the upper limbs measured with the PUL test. Moreover, all …