Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …

G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
higher level of genetically determined Lp(a) levels was associated with 22% greater risk of
myocardial infarction… cases genotyped for ≈49 000 genetic variants in 2100 candidate genes, …

Very low lipoprotein (a) and increased mortality risk after myocardial infarction

P Wohlfahrt, D Jenča, V Melenovský… - European Journal of …, 2021 - Elsevier
… data and genetic studies proved the association of elevated Lp(a) with increased risk of …
Our finding that elevated L(a) is associated with increased risk of total mortality and …

Elevated LDL cholesterol and increased risk of myocardial infarction and atherosclerotic cardiovascular disease in individuals aged 70–100 years: a contemporary …

MB Mortensen, BG Nordestgaard - The Lancet, 2020 - thelancet.com
Background Findings of historical studies suggest that elevated LDL cholesterol is not associated
with increased risk of myocardial infarction and atherosclerotic cardiovascular disease …

Equivalent impact of elevated lipoprotein (a) and familial hypercholesterolemia in patients with atherosclerotic cardiovascular disease

BS Hedegaard, CS Bork, M Kaltoft, IC Klausen… - Journal of the American …, 2022 - jacc.org
… Individuals with both elevated lipoprotein(a) and either … of premature myocardial infarction
had a higher risk of myocardialrisk in terms of 2 different genetically elevated lipoproteins, that …

Lipoprotein (a) as part of the diagnosis of clinical familial hypercholesterolemia

A Langsted, BG Nordestgaard - Current Atherosclerosis Reports, 2022 - Springer
Elevated lipoprotein(a) is a risk factor for cardiovascular diseases such as myocardial infarction
and … In 2009, genetic variation through KIV2 number of repeats in LPA explained a large …

Atherosclerotic cardiovascular disease risk and elevated lipoprotein (a) among young adults with myocardial infarction: The Partners YOUNG-MI Registry

AN Berman, DW Biery, A Singh, WY Wu… - European journal of …, 2021 - academic.oup.com
… Given its genetic underpinnings, levels of Lp(a) are relatively stable … risk, Lp(a) levels, and
future ASCVD events – specifically, in individuals who have had a myocardial infarction (MI) at …

Lipoprotein (a) and cardiovascular disease

BG Nordestgaard, A Langsted - The Lancet, 2024 - thelancet.com
… are more than 90% genetically determined and 17% higher in post-menopausal women than
in men. Individuals at a higher cardiovascular risk should have lipoprotein(a… those with high

Lipoprotein (a) and cardiovascular disease

PR Kamstrup - Clinical chemistry, 2021 - academic.oup.com
high lipoprotein(a) concentrations gained from large genetic … generally demonstrated increased
risk at high concentrations… for atherosclerotic disease and myocardial infarction (MI) (27, …

Low lipoprotein (a) levels and risk of disease in a large, contemporary, general population study

A Langsted, BG Nordestgaard… - European heart …, 2021 - academic.oup.com
… and genetically low levels of lipoprotein(a) with decreased risk of myocardial infarction, aortic
… with causal associations of high lipoprotein(a) levels with increased risk of cardiovascular …

Elevated lipoprotein (a) and risk of atrial fibrillation: an observational and mendelian randomization study

P Mohammadi-Shemirani, M Chong, S Narula… - Journal of the American …, 2022 - jacc.org
genetic analyses, our results implicate Lp(a) as a potentially causal mediator of AF. Higher
Lp(a) levels were associated with a greater risk … namely stroke and myocardial infarction, and …