Genistein: its role in breast cancer growth and metastasis

V Mukund - Current drug metabolism, 2020 - ingentaconnect.com
angiogenesis in mice have been inhibited by soy-rich diets of humans. [20, 21]. Genistein
conducted through in vivo experiments, the molecular processes of genistein should be well …

[HTML][HTML] Antiangiogenic phytochemicals constituent of diet as promising candidates for chemoprevention of cancer

AD Marrero, AR Quesada, B Martínez-Poveda… - Antioxidants, 2022 - mdpi.com
… Interestingly, recent evidence supports the ability of genistein, … addition, genistein is also a
potent inhibitor of angiogenesis, … a multitarget inhibitor of angiogenesis in vitro and in vivo [168,…

[HTML][HTML] Molecular changes underlying Genistein treatment of wound healing: a review

M Čoma, V Lachová, P Mitrengová, P Gál - Current Issues in Molecular …, 2021 - mdpi.com
… Furthermore, an in vivo study showed that genistein treatment can … Genistein was also able
to inhibit inducible nitric oxide synthase (… Furthermore, genistein modulated angiogenesis by …

[HTML][HTML] Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway

WX Cheng, H Huang, JH Chen, TT Zhang… - Journal of orthopaedic …, 2020 - Elsevier
Genistein (GEN), a soy-derived isoflavone, has been validated that can effectively inhibit the
angiogenesis of several tumours. We thus carried out a study in vitro to investigate the effect …

[HTML][HTML] (R, S)-Equol 7-β-D-glucuronide, but not other circulating isoflavone metabolites, modulates migration and tubulogenesis in human aortic endothelial cells …

JA Giménez-Bastida, MÁ Ávila-Gálvez… - Food & Function, 2024 - pubs.rsc.org
… We aimed here to first assess the anti-angiogenic activities of … and their conjugated metabolites
of genistein and daidzein. … -II metabolite with the ability to inhibit tubulogenesis in vitro. …

Nutraceuticals and their role in tumor angiogenesis

A Rampino, T Annese, A Margari, R Tamma… - Experimental Cell …, 2021 - Elsevier
Genistein is a isoflavone that inhibits the proliferation and migration … vitro angiogenic and
metastatic potential of different tumor cell lines [65]. Moreover, genistein inhibits angiogenesis

[PDF][PDF] Food & Function

JA Giménez-Bastida, MÁ Ávila-Gálvez… - novaresearch.unl.pt
… We aimed here to first assess the anti-angiogenic activities of … and their conjugated metabolites
of genistein and daidzein. … (ii) modulation of in vitro angiogenic mechanisms in this cell …

[HTML][HTML] Angioprevention of urologic cancers by plant-derived foods

M García-Caballero, JA Torres-Vargas, AD Marrero… - Pharmaceutics, 2022 - mdpi.com
… In vitro, genistein inhibits endothelial cell … of genistein is mediated by the inhibition of
HIF pathway in pancreatic carcinoma cells [207] and by down-regulation of the pro-angiogenic

Pro‐Angiogenic and Anti‐Angiogenic Effects of Phytochemicals as Nutraceuticals

V Kumar, S Ghosh, S Saini, H Agrawal… - … of Nutraceuticals and …, 2022 - Wiley Online Library
… and concentrations used in vitro and in vivo to analyze their angiogenic potential in some …
Genistein is an isoflavonic phytoestrogen mainly available in soybeans. It can downregulate …

[HTML][HTML] Antiangiogenic activity of flavonoids: a systematic review and meta-analysis

M Khater, F Greco, HMI Osborn - Molecules, 2020 - mdpi.com
… different in vitro and/or in/ex vivo angiogenesis assays that have been used; Section 2 is a
meta-analysis study of a quantitatively comparative subset of data, based on the in vivo chick …