Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19

MJ Corley, APS Pang, K Dody, PA Mudd… - Journal of leukocyte …, 2021 - academic.oup.com
… Here, we examined genome-wide DNA methylation (DNAm) profiles of peripheral blood
mononuclear cells from 9 terminally-ill, critical COVID-19 patients with confirmed SARS-CoV-2 …

DNA methylation profiling: an emerging paradigm for cancer diagnosis

A Papanicolau-Sengos, K Aldape - Annual Review of Pathology …, 2022 - annualreviews.org
DNA methylation profiling is an additional emerging tool that … Genome-wide interrogation of
DNA methylation signatures, in … Tumor DNA methylation profiling has led to the identification …

DNA methylation profiling of human hepatocarcinogenesis

G Hernandez‐Meza, J von Felden… - …, 2021 - Wiley Online Library
DNA methylation changes across the different histological stages of human
hepatocarcinogenesis. To do so, we analyzed genomewide DNA methylation profiles … and …

[HTML][HTML] Clinical epigenomics: genome-wide DNA methylation analysis for the diagnosis of Mendelian disorders

B Sadikovic, MA Levy, J Kerkhof, E Aref-Eshghi… - Genetics in …, 2021 - nature.com
… We describe the clinical implementation of genome-wide DNA methylation analysis in rare
disorders across the EpiSign diagnostic laboratory network and the assessment of results …

[HTML][HTML] Distinct epigenetic features of tumor-reactive CD8+ T cells in colorectal cancer patients revealed by genome-wide DNA methylation analysis

R Yang, S Cheng, N Luo, R Gao, K Yu, B Kang… - Genome biology, 2020 - Springer
… Our in-depth methylation profiling identified the specific demethylation status … broad but
undefined effect on the genome [39]. Advances in techniques for manipulating DNA methylation

[HTML][HTML] Genome-wide DNA methylation meta-analysis in the brains of suicide completers

S Policicchio, S Washer, J Viana, A Iatrou… - Translational …, 2020 - nature.com
… . Previously, our group performed DNA methylation profiling in these samples 22 and the
results of that study were included in this meta-analysis study. To examine whether our …

[HTML][HTML] Gene set enrichment analysis for genome-wide DNA methylation data

J Maksimovic, A Oshlack, B Phipson - Genome Biology, 2021 - Springer
… Here we present GOmeth and GOregion to perform gene set analysis in the context of DNA
methylation array data for differential methylation of CpG sites and regions, respectively. The …

[HTML][HTML] Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

MF Nabais, SM Laws, T Lin, CL Vallerga, NJ Armstrong… - Genome biology, 2021 - Springer
methylated positions (DMPs), we applied mixed-linear model-based association studies of
DNA methylation … —with profile scores derived from CTP and DNA methylation effect sizes—…

[HTML][HTML] DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse

W Zhou, T Hinoue, B Barnes, O Mitchell, W Iqbal… - Cell genomics, 2022 - cell.com
… We have developed a mouse DNA methylation array that contains 296,070 … DNA methylation
biology. We present a mouse methylation atlas as a rich reference resource of 1,239 DNA

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
… emerging DNA methylationgenome-wide DNA methylation profiling techniques. These
approaches hold promise for facilitating our comprehensive understanding of DNA methylation