[HTML][HTML] Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort☆
… Case-control analysis identified signals showing p values ≤5 × 10 −8 at 4 locations (chromosome
[chr] 2 GCKR/C2ORF16; chr4 HSD17B13; chr19 TM6SF2; chr22 PNPLA3) together …
[chr] 2 GCKR/C2ORF16; chr4 HSD17B13; chr19 TM6SF2; chr22 PNPLA3) together …
Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities
… experimental studies are genome-wide association studies (… alternative approach to identify
new genes and pathways that … In 2011, we identified a locus near IRS1 of which the body-fat-…
new genes and pathways that … In 2011, we identified a locus near IRS1 of which the body-fat-…
Genome‐wide association study and meta‐analysis on alcohol‐associated liver cirrhosis identifies genetic risk factors
TH Schwantes‐An, R Darlay, P Mathurin… - …, 2021 - Wiley Online Library
… To identify additional genetic associations, we performed a … for variants in the two genomewide
significant loci (rs4607179 for … analysis identified genome- wide significant association for …
significant loci (rs4607179 for … analysis identified genome- wide significant association for …
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological …
…, JI Rotter, JA Lynch, Regeneron Genetics Center… - … genetics, 2022 - nature.com
… and ancestry-specific genome-wide association scans. The orange box of the … -analyses
identifying 77 multiancestry loci + 1 EA-specific locus + 2 AA-specific loci that met genome-wide …
identifying 77 multiancestry loci + 1 EA-specific locus + 2 AA-specific loci that met genome-wide …
Genome-wide analysis identifies novel susceptibility loci for myocardial infarction
… We carried out a genome-wide association study for MI in … analysis identified 1966
single-nucleotide polymorphisms (SNPs) at 31 loci that were associated with MI at the genome-wide …
single-nucleotide polymorphisms (SNPs) at 31 loci that were associated with MI at the genome-wide …
[HTML][HTML] Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging
…, C Gieger, Genetics of DNA Methylation Consortium… - Genome biology, 2021 - Springer
… identify 137 genome-wide significant loci, of which 113 are novel, from genome-wide association
study (GWAS) meta-analyses … We find evidence for shared genetic loci associated with …
study (GWAS) meta-analyses … We find evidence for shared genetic loci associated with …
[HTML][HTML] The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study
… Here we conducted a genome-wide association study (GWAS) with … Our analysis identified
an additional 107 loci that were significant at the GWS level in the between-sex meta-analysis …
an additional 107 loci that were significant at the GWS level in the between-sex meta-analysis …
[HTML][HTML] Genome-and transcriptome-wide association studies provide insights into the genetic basis of natural variation of seed oil content in Brassica napus
… Here, we decipher the genetic basis of natural variation in SOC of Brassica napus by genome-
and transcriptome-wide association studies using 505 inbred lines. We mapped reliable …
and transcriptome-wide association studies using 505 inbred lines. We mapped reliable …
[HTML][HTML] Genome-wide association studies
… identifying regulatory target genes of genetic variants is molecular quantitative trait loci (molQTLs)
analysis, which associates genetic … example, eQTL analysis identifies loci associated …
analysis, which associates genetic … example, eQTL analysis identifies loci associated …
[HTML][HTML] Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
… Combining data for up to 703,901 individuals from 51 studies in a multi-ancestry meta-analysis
of genome-wide association studies yields 99 loci that associate with self-reported …
of genome-wide association studies yields 99 loci that associate with self-reported …