Alterations in DNA methylation profiles in cancellous bone of postmenopausal women with osteoporosis
Y Zhou, L Yang, H Wang, X Chen, W Jiang… - FEBS Open …, 2020 - Wiley Online Library
… methylation microarray analysis of the hip cancellous bone of patients with osteoarthritis
revealed differential methylation. … bone in bone development, we examined genome-wide DNA …
revealed differential methylation. … bone in bone development, we examined genome-wide DNA …
Comparative profiles of DNA methylation and differential gene expression in osteocytic areas from aged and young mice
Y Wei, J Fu, W Wu, J Wu - Cell Biochemistry and Function, 2020 - Wiley Online Library
… factors in age-related bone loss, either together or individually. … the differentially methylated
regions (DMRs), differentially … studies have revealed that SCFAs can improve the bone loss …
regions (DMRs), differentially … studies have revealed that SCFAs can improve the bone loss …
DNA methylation signatures of bone metabolism in osteoporosis and osteoarthritis aging-related diseases: an updated review
VV Visconti, I Cariati, S Fittipaldi, R Iundusi… - International Journal of …, 2021 - mdpi.com
… in bone biopsies from postmenopausal OP women, revealing … Profiling analysis identified
7316 differentially methylated … However, these differentially methylated regions of the genome …
7316 differentially methylated … However, these differentially methylated regions of the genome …
Genome‐wide DNA methylation profile analysis in thoracic ossification of the ligamentum flavum
T Fan, X Meng, C Sun, X Yang, G Chen… - Journal of Cellular …, 2020 - Wiley Online Library
… shortlisted the differentially methylated GO terms functionally related to bone development,
… shown to have distinct epigenomic profiles, and the Venn diagram revealed 65 significantly …
… shown to have distinct epigenomic profiles, and the Venn diagram revealed 65 significantly …
A road map for understanding molecular and genetic determinants of osteoporosis
… 53,54 have reported that genetic profiling of BMD-associated … of human bone detected 241
differentially methylated CpG … human osteoblasts and osteocytes revealed that the genes that …
differentially methylated CpG … human osteoblasts and osteocytes revealed that the genes that …
Genome-wide methylation changes associated with replicative senescence and differentiation in endothelial and bone marrow mesenchymal stromal cells
A Giuliani, MG Bacalini, D Ramini, E Mensà… - Cells, 2023 - mdpi.com
… senescence-associated DMPs revealed 16 common pathways… bone loss and reducing the
regenerative capacity of tissues. … a differential methylation of genes involved in bone formation …
regenerative capacity of tissues. … a differential methylation of genes involved in bone formation …
Lipid Metabolism, Methylation Aberrant, and Osteoporosis: A Multi-omics Study Based on Mendelian Randomization
ZL Zhang, YC Duan, JZ Huo - Calcified Tissue International, 2024 - Springer
… of lipid profile-associated methylation sites and bone mineral … also showed that differential
methylation profiles in whole … of osteoporosis, suggesting that methylation regulation also …
methylation profiles in whole … of osteoporosis, suggesting that methylation regulation also …
Identification of Key Osteoporosis Genes Through Comparative Analysis of Men's and Women's Osteoblast Transcriptomes
D Chen, Y Li, Q Wang, P Zhan - Calcified Tissue International, 2023 - Springer
… the bone methylome and encompass sites linked to bone regulation [29]. We analyzed blood
methylation data and identified 451 differentially methylated … transcriptome also revealed its …
methylation data and identified 451 differentially methylated … transcriptome also revealed its …
Identification of genes with altered methylation in osteoclast differentiation and its roles in osteoporosis
R Peng, Y Dong, H Kang, Q Guo, M Zhu… - DNA and Cell Biology, 2022 - liebertpub.com
… to excessive bone resorption and massive bone loss, which … differentially expressed genes
with differential methylation … In another expression profile, ROC curve analysis revealed that …
with differential methylation … In another expression profile, ROC curve analysis revealed that …
Multi-modal molecular determinants of clinically relevant osteoporosis subtypes
C Yuan, XT Yu, J Wang, B Shu, XY Wang, C Huang… - Cell Discovery, 2024 - nature.com
… , osteoporosis and the associated risk of bone fractures have … should help reveal the global
and complete characteristics of … These findings suggest that the methylation profile is capable …
and complete characteristics of … These findings suggest that the methylation profile is capable …