Epigenetic regulation of skeletal tissue integrity and osteoporosis development
YS Chen, WS Lian, CW Kuo, HJ Ke, SY Wang… - International Journal of …, 2020 - mdpi.com
… methylation, microRNA, and histone modification and highlights their interactions during
skeletal development and bone loss … revealed that over 500 gene loci are associated with bone …
skeletal development and bone loss … revealed that over 500 gene loci are associated with bone …
Associations between epigenome-wide DNA methylation and height-related traits among Sub-Saharan Africans: the RODAM study
G Swart, K Meeks, F Chilunga, A Venema… - … Origins of Health and …, 2023 - cambridge.org
… hypothesized as contributing to osteoporosis as well as other … Epigenetic profiles derived
from bone-related tissues would … differentially methylated region identified HOXA cluster gene …
from bone-related tissues would … differentially methylated region identified HOXA cluster gene …
Epigenetics of Osteoporosis
O Bischof, R Ebert, H Taipaleenmäki, E Hesse… - …, 2021 - thieme-connect.com
… Impaired bone formation, accelerated bone loss, and … blood leukocytes from osteoporosis
patients that reveal novel disease … CpG islands differentially methylated in osteoporosis versus …
patients that reveal novel disease … CpG islands differentially methylated in osteoporosis versus …
Identification of ferroptosis-associated biomarkers for the potential diagnosis and treatment of postmenopausal osteoporosis
Y Hu, J Han, S Ding, S Liu, H Wang - Frontiers in Endocrinology, 2022 - frontiersin.org
… To prevent bone loss, a proactive approach is recommended … We then curated the expression
profiles of the DEFAGs for … OP can be revealed through the study of OP candidate gene …
profiles of the DEFAGs for … OP can be revealed through the study of OP candidate gene …
[HTML][HTML] Reduced CpG island methylation of the TBC1D8 gene may predict risk for osteoporosis in Chinese postmenopausal women
QQ Ma, L Lin, Q Yao, J Yang, Y Hu, JB Yu - Oncotarget, 2020 - ncbi.nlm.nih.gov
… Study that contained 7633 Caucasian women and 3657 men revealed that 2q 11.2 of …
differences in genome wide methylation in bone cells from the femoral head region of patients with …
differences in genome wide methylation in bone cells from the femoral head region of patients with …
Role of epigenetic regulatory mechanisms in age‐related bone homeostasis imbalance
Y Zhong, X Zhou, Z Pan, J Zhang, J Pan - The FASEB Journal, 2024 - Wiley Online Library
… Recent studies on bone aging have revealed that cytokine … aging- associated differentially
methylated regions. Generally… be inhibited in osteoporosis or agerelated bone loss, and is …
methylated regions. Generally… be inhibited in osteoporosis or agerelated bone loss, and is …
Screening and Analysis of Core Genes for Osteoporosis Based on Bioinformatics Analysis and Machine Learning Algorithms
Y Lu, W Wang, B Yang, G Cao, Y Du, JY Liu - Indian Journal of …, 2024 - Springer
… mRNA expression profiles of osteoporosis patients were … Osteoporosis (OP) is a prevalent
bone disease that reduces … Further investigations reveal that reducing miR-133a levels inhibits …
bone disease that reduces … Further investigations reveal that reducing miR-133a levels inhibits …
Prioritization of genes relevant to bone fragility through the unbiased integration of aging mouse bone transcriptomics and human GWAS analyses
… imbalanced bone remodeling and progressive bone loss, … profile in aging bone, pathway
analysis revealed few … DEGs in each aging gene set were most enriched for the same KEGG …
analysis revealed few … DEGs in each aging gene set were most enriched for the same KEGG …
Precision Medicine: Pharmacogenetics and Pharmacogenomics of Osteoporosis
Y El Miedany - New Horizons in Osteoporosis Management, 2022 - Springer
… in bone, there is still an unmet gap in our knowledge about pharmacogenomics and
pharmacogenetics of osteoporosis… in osteoporosis treatment by comparing the expression profiles …
pharmacogenetics of osteoporosis… in osteoporosis treatment by comparing the expression profiles …
Transcriptome-wide m6A methylome during osteogenic differentiation of human adipose-derived stem cells
… of bone biology, m 6 A modification plays critical roles in bone development as well as bone
diseases such as osteoporosis… these differentially methylated and regulated genes revealed …
diseases such as osteoporosis… these differentially methylated and regulated genes revealed …