Rare variant analysis of obesity-associated genes in young adults with severe obesity from a consanguineous population of Pakistan

S Saeed, QM Janjua, A Haseeb, R Khanam… - Diabetes, 2022 - Am Diabetes Assoc
obesity-associated traits by genome-wide association studies. … , large genome-wide association
studies (GWAS) identified … ≥35 kg/m 2 , early-onset obesity, and hyperphagia within the …

[HTML][HTML] Evaluation of the MC4R gene across eMERGE network identifies many unreported obesity-associated variants

B Namjou, IB Stanaway, T Lingren, FD Mentch… - … Journal of Obesity, 2021 - nature.com
early onset obesity and hyperphagia [6]. MC4R-associated … surrounding MC4R and
genome-wide association of BMI, … codes related to overweight, obesity, and morbid obesity (best …

[HTML][HTML] Rare variants in genes linked to appetite control and hypothalamic development in early-onset severe obesity

P Loid, T Mustila, RE Mäkitie, H Viljakainen… - Frontiers in …, 2020 - frontiersin.org
… , including twin studies, genome-wide association studies (GWASs), … early-onset obesity are
likely to be related to the identified … A linkage analysis in French families with morbid obesity

[HTML][HTML] The analysis of a genome-wide association study (GWAS) of overweight and obesity in psoriasis

A Kisielnicka, M Sobalska-Kwapis… - International Journal of …, 2022 - mdpi.com
… among psoriatic patients may lead to significant clinical consequences, mainly early onset
… detailed genetic studies include identifying patients with an increased risk of obesity among …

Adolescent obesity and early-onset type 2 diabetes

G Twig, I Zucker, A Afek, T Cukierman-Yaffe… - Diabetes …, 2020 - Am Diabetes Assoc
… associated with high rates of morbidity, hospitalization, health … identify early abnormal weight
gain patterns, and to direct health care policy in the evaluation and management of obesity

[HTML][HTML] Large-scale exome sequence analysis identifies sex-and age-specific determinants of obesity

LR Kaisinger, KA Kentistou, S Stankovic, EJ Gardner… - Cell genomics, 2023 - cell.com
… of common variant genome-wide pathway enrichment … It is associated with increased
mortality and morbidity as well … Meta-analysis of genome-wide association studies for height …

[HTML][HTML] Genome-wide association study identifies genetic risk loci for adiposity in a Taiwanese population

HSC Wong, SY Tsai, HW Chu, MR Lin, GH Lin… - PLoS …, 2022 - journals.plos.org
… , the obesity-related genetic loci identified here provide new … These measurements associate
with various morbidities, such … (three of four; 75%) were identified for early-onset extreme …

[HTML][HTML] New insights from GWAS on BMI-related growth traits in a longitudinal cohort of admixed children with Native American and European ancestry

L Vicuña, E Barrientos, T Norambuena, D Alvares… - Iscience, 2023 - cell.com
… The few genome-wide association studies (GWAS) on children have been performed …
Genome-wide association study for early-onset and morbid adult obesity identifies three new

[HTML][HTML] Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity

A Bairqdar, E Shakhtshneider, D Ivanoshchuk… - Journal of Personalized …, 2023 - mdpi.com
… The increase in the prevalence of overweight, obesity and associated diseases is … study
was to identify rare variants in obesity-associated genes in young adults with abdominal obesity

New insights from GWAS on longitudinal and cross-sectional BMI and related phenotypes in admixed children with Native American and European ancestries

L Vicuña, E Barrientos, T Norambuena, D Alvares… - medRxiv, 2021 - medrxiv.org
… , according to a genome-wide association study (GWAS) meta… We identified additional
association peaks at chromosomes 4 … of genome-wide association studies for early-onset extreme …