[HTML][HTML] A genome-wide association study of dementia using the electronic medical record

X Cao, Y Dong, L Xing, X Zhang - BioMedInformatics, 2023 - mdpi.com
… , we conducted a Genome-Wide Association Study (GWAS) … This study has two aims, (1)
to investigate the genetic … study involving intellectual disability, autism and psychosis, …

Genome-wide association, Mendelian Randomization and polygenic risk score studies converge on a role of β−amyloid and APOE locus in Parkinson disease

L Ibanez, JA Bahena, C Yang, U Dube, FG Farias… - medRxiv, 2020 - medrxiv.org
Alzheimer disease (AD); its use as quantitative traits in genetic … Here, genome-wide association
studies (GWAS) were … method described by the Psychiatric Consortium 45 and ourselves…

The genome-wide risk alleles for psychiatric disorders at 3p21. 1 show convergent effects on mRNA expression, cognitive function, and mushroom dendritic spine

Z Yang, D Zhou, H Li, X Cai, W Liu, L Wang… - Molecular …, 2020 - nature.com
… Here, we conduct summary data-based Mendelian randomization (SMR) analyses
through combining the statistical data from genome-wide association studies (GWAS) of both …

Efficacy difference of antipsychotics in Alzheimer's disease and schizophrenia: explained with network efficiency and pathway analysis methods

P Fan, J Kofler, Y Ding, M Marks… - Briefings in …, 2022 - academic.oup.com
genome-wide association study (GWAS) to identify risk loci for AD+P compared with AD-P
patients … liability to cognitive and psychotic symptoms in Alzheimer disease and schizophrenia, …

[HTML][HTML] A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders

EO Adewuyi, EK O'Brien, DR Nyholt, T Porter… - Communications …, 2022 - nature.com
… ) disorders; however, their underlying mechanisms remain unclear. Here, we analyse several
genome-wide association studies (… relationship of AD with GIT disorders. Findings reveal a …

Alzheimer's Disease-Related Psychosis: An Overview of Clinical Manifestations, Pathogenesis, and Current Treatment

AY Benmelouka, Y Ouerdane, O Outani… - … Alzheimer Research, 2022 - ingentaconnect.com
… In this study sample, genomewide and chromosome-wide linkage peaks were significantly
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease. Mol …

[HTML][HTML] X chromosome-wide association study of quantitative biomarkers from the Alzheimer's Disease Neuroimaging Initiative study

…, Alzheimer's Disease Neuroimaging … - Frontiers in Aging …, 2023 - ncbi.nlm.nih.gov
… the Alzheimer’s Disease Neuroimaging Initiative Study, we conducted an X chromosome-wide
association studygenome-wide association studies (GWAS) for the disease modeling. …

Genome-wide association study (GWAS)

MA Simonson - Encyclopedia of Behavioral Medicine, 2020 - Springer
… for common disease utilizes knowledge gleaned from genetic association studies and should
Genome-wide association studies are designed to identify points of common variation in …

Genome-wide association study identifies 48 common genetic variants associated with handedness

G Cuellar-Partida, JY Tung, N Eriksson… - Nature human …, 2021 - nature.com
… suggest that handedness is highly polygenic and that the genetic variants that predispose
to left-handedness may underlie part of the association with some psychiatric disorders. …

[HTML][HTML] Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects

L Krohn, K Heilbron, C Blauwendraat… - Nature …, 2022 - nature.com
… Here, we perform a genome-wide association study of RBD, identifying five RBD risk loci
near SNCA, GBA, TMEM175, INPP5F, and SCARB2. Expression analyses highlight SNCA-AS1 …