Genome-Wide DNA Methylation Profile Reveals Potential Therapeutic Targets at the Late Stage of Knee Osteoarthritis
H Shen, J Long, M Zhang, X Chen, T Wang, Q Xie… - 2020 - researchsquare.com
… have been reported, revealing differentially methylated (DM) … as the interference of osteoporosis
caused by different ages. … knee cartilage reveals embryonic organ and skeletal system …
caused by different ages. … knee cartilage reveals embryonic organ and skeletal system …
[HTML][HTML] Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis
Y Jia, X Qi, M Ma, S Cheng, B Cheng… - Bone & Joint …, 2023 - boneandjoint.org.uk
… rSNPs has the potential to reveal novel susceptibility genetic … In a study of transcriptional
profiling of human femoral MSCs … cartilage loss in knees with osteoarthritis. Furthermore, a cross…
profiling of human femoral MSCs … cartilage loss in knees with osteoarthritis. Furthermore, a cross…
The association between knee synovial methylation and knee osteoarthritis in different ethnic populations from different altitude
Z Li, D Zhang, R Ren, Z Lu, G Li, T Geng, J Luosong… - 2024 - researchsquare.com
… of separating OA studies from skeletal sites and help us … chip was used to screen and analyze
the differential methylation sites to … To determine genome-wide DNA methylation profiles of …
the differential methylation sites to … To determine genome-wide DNA methylation profiles of …
[PDF][PDF] Role of Epigenetics in Bone and Cartilage
JBJ van Meurs, CG Boer - genetics and phenotypes in all their …, 2020 - repub.eur.nl
… found enrichment of differentially methylated CpGs in enhancer regions [53]. … Genome-wide
profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis. …
profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis. …
[HTML][HTML] Osteoarthritis year in review: genetics, genomics, epigenetics
… Main Upset plot shows number of publications (≥3) with … This year saw a dearth of large
genome-wide association … an increased risk of osteoporosis and lower bone mineral density (…
genome-wide association … an increased risk of osteoporosis and lower bone mineral density (…
[HTML][HTML] Osteoarthritis year in review 2022: Genetics, genomics and epigenetics
M Kim, A Rubab, WCW Chan, D Chan - Osteoarthritis and Cartilage, 2023 - Elsevier
… This is in concordance with the genome wide association … relationship between OA and
osteoporosis that is complex … showed that Lrrc15 is differentially methylated and expressed in OA …
osteoporosis that is complex … showed that Lrrc15 is differentially methylated and expressed in OA …
[HTML][HTML] DNA methylation of noncoding RNAs: new insights into osteogenesis and common bone diseases
… genome-wide DNA methylation to study the development of knee osteoarthritis; identified
DNA methylation … The degree of DNA methylation in the differentially methylated regions …
DNA methylation … The degree of DNA methylation in the differentially methylated regions …
Identification of Key Osteoporosis Genes Through Comparative Analysis of Men's and Women's Osteoblast Transcriptomes
D Chen, Y Li, Q Wang, P Zhan - Calcified Tissue International, 2023 - Springer
… -related diseases, including osteoporosis and osteoarthritis. … collection of all human
genome-wide association studies, and … methylation data and identified 451 differentially …
genome-wide association studies, and … methylation data and identified 451 differentially …
[HTML][HTML] DNA methylation and noncoding RNA in OA: Recent findings and methodological advances
V Izda, J Martin, C Sturdy, MA Jeffries - Osteoarthritis and cartilage open, 2021 - Elsevier
… in OA cartilage (Overview of differentially methylated pathways from studies included in …
genome-wide DNA methylation patterns in right distal femoral cartilage and subchondral bone of …
genome-wide DNA methylation patterns in right distal femoral cartilage and subchondral bone of …
[HTML][HTML] Insights into the molecular landscape of osteoarthritis in human tissues
… with osteoarthritis, large-scale genome-wide association … This study compared subchondral
bone underlying low-… heart disease and cluster C with osteoporosis [43] . Replication of the …
bone underlying low-… heart disease and cluster C with osteoporosis [43] . Replication of the …