… In the results of genome-wide methylation, there was no … 4E, the next step of the differential
methylation analysis was … interruptions, bone disorders and unclear bones in some areas. …

… of many skeletal diseases, including osteoporosis. However, … predictions agree with those
of genome-wide in vitro assays (Hi… 2 shows examples of genetic models for human skeletal …

… In this study, we identified four novel genome-wide significant loci by a … Bone mineral density,
osteoporosis, and osteoporotic … in human osteoarthritis. Cartilage 2021;13:1431s–41S. 46. …

… of NELL1 in diseases and treatments revealed by GWASs. … NELL-1 has therapeutic potential
in osteoarthritis due to its pro-… Osteoporosis is an aging-related bone-degenerative disease …

… (ChIP-Seq) allows genome-wide discovery of protein–DNA … with the regulation of skeletal
muscle, cell proliferation, and … been associated with osteoarthritis and osteoporosis. Mutations …

… In conclusion, our data reveal that AC008 plays a critical role … LncRNA-CRNDE regulates
chondrogenic differentiation of bone … investigated the lncRNA expression profiles of normal and …

… Notably, recent studies have revealed subchondral bone lesions … bone resorption, subsequent
imbalances in bone metabolism, accelerated bone turnover, and a decrease in bone …

… Therefore, this study aimed to generate a profile of global differential gene expression involved
… Recent studies have shown that in bone diseases in humans, such as osteoarthritis and …

… The authors identified 500 differentially methylated CpG sites in the muscle cells of old …
osteoporosis (OP) and osteoarthritis (OA). Genome-wide analysis comparing DNA methylation …

… Previously, our ability to identify differentially methylated regions … males and females with
osteoarthritis or osteoporosis, were … genome-wide mean of measured methylation in the Bone 2 …