Identification of biomarkers associated with diagnosis of postmenopausal osteoporosis patients based on bioinformatics and machine learning
X Huang, J Ma, Y Wei, H Chen, W Chu - Frontiers in Genetics, 2023 - frontiersin.org
… in patients with knee osteoarthritis were higher than those in the … expression in postmenopausal
osteoporosis bone tissues … RBCK1 were identified as differentially methylated genes. All …
osteoporosis bone tissues … RBCK1 were identified as differentially methylated genes. All …
Epigenome-wide association study reveals a molecular signature of response to phylloquinone (vitamin K1) supplementation
K Westerman, JM Kelly, JM Ordovás, SL Booth… - Epigenetics, 2020 - Taylor & Francis
… We identified differential methylation at both known and novel loci, … Genome-wide analysis
revealed two differentially … For example, osteocalcin (OC) is a protein synthesized in bone that …
revealed two differentially … For example, osteocalcin (OC) is a protein synthesized in bone that …
Organ-and Site-Specific HOX Gene Expression in Stromal Cells
M Mirrahimi, C Ospelt - Fibroblasts-Advances in Inflammation …, 2021 - books.google.com
… Genome-wide gene expression profile of 47 fibroblast … in the skeletal muscle lineage [34].
Analysis of DNA … ated with the onset and development of osteoarthritis (OA)(eg HOXA9 in hip …
Analysis of DNA … ated with the onset and development of osteoarthritis (OA)(eg HOXA9 in hip …
[HTML][HTML] Emerging roles of long non-coding RNAs in osteonecrosis of the femoral head
Z Li, C Huang, B Yang, W Hu, MTV Chan… - American Journal of …, 2020 - ncbi.nlm.nih.gov
… conditions, eg osteoporosis [12], osteoarthritis [13], … at the genome-wide level by RNA
sequencing or microarray in osteonecrotic tissues, mesenchymal stem cells (MSCs) and bone …
sequencing or microarray in osteonecrotic tissues, mesenchymal stem cells (MSCs) and bone …
Hypermethylation within the ALOX12 and CBS Promoters in a Rat Model of Osteoporosis and Human Osteoporosis Patients: Potential Biomarkers for an Early …
S Guo, Y Wu, W Chia, P Hsu, H Wang, Y Wang… - ALOX12 - papers.ssrn.com
… Bisulfite conversion and qMSP analyses revealed the methylation … osteoporosis that was
associated with a decreased bone … genome-wide alterations of quantifiable epigenetic marks, …
associated with a decreased bone … genome-wide alterations of quantifiable epigenetic marks, …
Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis
C Medina-Gomez, BH Mullin, A Chesi… - Communications …, 2023 - nature.com
… primary diagnostic marker for osteoporosis and fracture risk … All individuals included in this
study had genome-wide array … due to hip fracture or osteoarthritis which were subjected to …
study had genome-wide array … due to hip fracture or osteoarthritis which were subjected to …
… accessibility and epigenetic deoxyribose nucleic acid (DNA) modifications in chronic kidney disease (CKD) osteoblasts: a study of bone and osteoblasts from …
A Martin, R Kawaguchi, Q Wang, IB Salusky… - JBMR Plus, 2024 - academic.oup.com
… detailed above to assess genome-wide chromatin accessibility. … Significantly differentially
methylated genes identified by … This study also revealed that CKD alters whole bone matrix …
methylated genes identified by … This study also revealed that CKD alters whole bone matrix …
Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling
… , bone, and skin, leading to osteoarthritis (OA), osteoporosis, … Our study shows that although
new protein incorporation … targets for osteoarthritis through genome- wide analyses of UK …
new protein incorporation … targets for osteoarthritis through genome- wide analyses of UK …
Epigenetics of the Aging Musculoskeletal System
B Slobodin - Rheumatic Disease in Geriatrics: Diagnosis and …, 2020 - Springer
… The authors identified 500 differentially methylated CpG sites in the muscle cells of old …
osteoporosis (OP) and osteoarthritis (OA). Genome-wide analysis comparing DNA methylation …
osteoporosis (OP) and osteoarthritis (OA). Genome-wide analysis comparing DNA methylation …
DNA methylation and expression of LGR6 gene in ankylosing spondylitis: A case-control study
Y Deng, W Xu, M Ni, X Sun, X Wang, T Zhang, F Pan - Human Immunology, 2023 - Elsevier
… A study involving genome-wide methylation revealed an … in the present study rather than
osteoarthritis [48]. Genotyping … Given the critical effect of LGR6 in regulating bone metabolism, …
osteoarthritis [48]. Genotyping … Given the critical effect of LGR6 in regulating bone metabolism, …