[HTML][HTML] Mediation analysis supports a causal relationship between maternal hyperglycemia and placental DNA methylation variations at the leptin gene locus and …
V Gagné-Ouellet, E Breton, K Thibeault… - International journal of …, 2020 - mdpi.com
… as the first 5 principal components as it was sufficient to bring genomic inflation close to 1 [28].
… made it possible to document the potential temporal stability of the reported DNAm marks …
… made it possible to document the potential temporal stability of the reported DNAm marks …
DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis
… epidemiological research applying mediation analyses. We … for the mediation analysis
using DNAm levels. However, we found heterogenous methods and interpretations in mediation …
using DNAm levels. However, we found heterogenous methods and interpretations in mediation …
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
… We first carried out a genome-wide association study (GWAS) of DNA methylation in peripheral
blood, … Our results thus identify UBASH3B as a potential mediator of both genetic and …
blood, … Our results thus identify UBASH3B as a potential mediator of both genetic and …
[HTML][HTML] Genetic impacts on DNA methylation: research findings and future perspectives
S Villicaña, JT Bell - Genome biology, 2021 - Springer
… However, growing evidence now shows that genetic variation also plays a role in the
establishment of DNA methylation marks, independently of or in contribution with environmental …
establishment of DNA methylation marks, independently of or in contribution with environmental …
[HTML][HTML] DNA methylation and regulation of gene expression: Guardian of our health
GA Dhar, S Saha, P Mitra, R Nag Chaudhuri - The Nucleus, 2021 - Springer
… , the DNA methylation pattern in the genome undergoes … a stable epigenetic mark, DNA
methylation is actually labile … by vitamin intake other than through mediation by DNMTs or TETs? …
methylation is actually labile … by vitamin intake other than through mediation by DNMTs or TETs? …
[HTML][HTML] DNA methylation: a potential mediator between air pollution and metabolic syndrome
… , we found that DNA methylation in neonatal blood is genome-wide significantly associated
… Studying these epigenetic marks together with their interplay with non-protein coding RNA …
… Studying these epigenetic marks together with their interplay with non-protein coding RNA …
[HTML][HTML] Role of DNA methylation in mediating genetic risk of psychiatric disorders
A Starnawska, D Demontis - Frontiers in Psychiatry, 2021 - frontiersin.org
… genome to mediate the risk of psychiatric disorders. The aim of this review is to explore the
putative role of DNA methylation … regulatory regions, epigenetic marks, and genes important …
putative role of DNA methylation … regulatory regions, epigenetic marks, and genes important …
Making it or breaking it: DNA methylation and genome integrity
… of DNA methylation in maintaining genome integrity in mammalian cells. DNA methylation is
a reversible epigenetic mark… DNMTs mediate the transfer of the labile methyl group (–CH 3 ) …
a reversible epigenetic mark… DNMTs mediate the transfer of the labile methyl group (–CH 3 ) …
DNA methylation as a mediator in the association between prenatal maternal stress and child mental health outcomes: Current state of knowledge
… DNA methylation of the NR3C1 gene. Youth mental health problems were also related to
NR3C1 hypermethylation … and did not detect significant mediation by DNA methylation though …
NR3C1 hypermethylation … and did not detect significant mediation by DNA methylation though …
[HTML][HTML] DNA methylation mediates the effect of maternal smoking on offspring birthweight: a birth cohort study of multi-ethnic US mother–newborn pairs
… by multiple epigenetic marks or on a genome-wide scale. As … of mediation and whether
it is causal although our mediation … of 38 differentially methylated CpG sites with genome-wide …
it is causal although our mediation … of 38 differentially methylated CpG sites with genome-wide …