Pseudomonas aeruginosa core metabolism exerts a widespread growth-independent control on virulence
S Panayidou, K Georgiades, T Christofi, S Tamana… - Scientific Reports, 2020 - nature.com
… offering optimized performance for pan-genome analyses. We used a local … Combinatorial
functional transcriptomics analysis at the pathway level was much more informative, revealing …
functional transcriptomics analysis at the pathway level was much more informative, revealing …
Combining antibiotics with antivirulence compounds can have synergistic effects and reverse selection for antibiotic resistance in Pseudomonas aeruginosa
C Rezzoagli, M Archetti, I Mignot, M Baumgartner… - PLoS …, 2020 - journals.plos.org
… As the combination treatments affect both growth and virulence factor production… combination
with ciprofloxacin and meropenem, where in both cases our sequencing analysis revealed …
with ciprofloxacin and meropenem, where in both cases our sequencing analysis revealed …
Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence
M Sultan, R Arya, KK Kim - International journal of molecular sciences, 2021 - mdpi.com
… aeruginosa infection and further develop new antibiotics to treat this pathogen. This review
discusses the important virulence factors of P. aeruginosa and the understanding of their …
discusses the important virulence factors of P. aeruginosa and the understanding of their …
Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype
JG Thöming, J Tomasch, M Preusse, M Koska… - npj Biofilms and …, 2020 - nature.com
… virulence phenotypes of a plethora of phylogenetically diverse clinical isolates of the opportunistic
pathogen Pseudomonas aeruginosa… enrichment analysis of upregulated genes shows …
pathogen Pseudomonas aeruginosa… enrichment analysis of upregulated genes shows …
Virulence Constitution of Multi-Drug-Resistant Pseudomonas aeruginosa in Upper Egypt
NA Hassuna, SA Mandour… - Infection and drug …, 2020 - Taylor & Francis
… aeruginosa showing a combination of adhesion and cytotoxicity … This study revealed
intermediate diversity of ERIC fingerprints, with 2 major clusters (1 and 2) enclosing 22 isolates, …
intermediate diversity of ERIC fingerprints, with 2 major clusters (1 and 2) enclosing 22 isolates, …
Virulence Factors of Pseudomonas Aeruginosa and Antivirulence Strategies to Combat Its Drug Resistance
C Liao, X Huang, Q Wang, D Yao, W Lu - … in cellular and infection …, 2022 - frontiersin.org
… virulence while sparing the bacterium for its eventual elimination by the immune system, or
combination … The arrows indicate a stimulatory effect, while the perpendicular line indicates …
combination … The arrows indicate a stimulatory effect, while the perpendicular line indicates …
Pseudomonas aeruginosa: a clinical and genomics update
…, C Mirande, A Oliver, P Moons… - FEMS Microbiology …, 2021 - academic.oup.com
… can infect most human organs and does so with virulence. In combination with MDR such
infections are troublesome to treat and present a menace to susceptible patient populations. …
infections are troublesome to treat and present a menace to susceptible patient populations. …
Hypermutator Pseudomonas aeruginosa exploits multiple genetic pathways to develop multidrug resistance during long-term infections in the airways of cystic fibrosis …
CA Colque, AG Albarracín Orio, S Feliziani… - Antimicrobial agents …, 2020 - Am Soc Microbiol
… This indicates that these mutations were positively selected … occur in CF patient sputum
and promote the virulence of P. … AmpC, in which the combination of distinct mutations may …
and promote the virulence of P. … AmpC, in which the combination of distinct mutations may …
[HTML][HTML] Genetic determinants of Pseudomonas aeruginosa fitness during biofilm growth
S Schinner, F Engelhardt, M Preusse, JG Thöming… - Biofilm, 2020 - Elsevier
… Advancing knowledge on P. aeruginosa adaptation to biofilm growth conditions is bound to
reveal novel strategies and targets for the treatment of chronic biofilm-associated infections. …
reveal novel strategies and targets for the treatment of chronic biofilm-associated infections. …
Pseudomonas aeruginosa reference strains PAO1 and PA14: A genomic, phenotypic, and therapeutic review
A Grace, R Sahu, DR Owen, VA Dennis - Frontiers in Microbiology, 2022 - frontiersin.org
… of two pathogenicity islands PAPI-1 and PAPI-2 in the genome of PA14. … is aerobic or
anaerobic, or a combination of both. … A number of studies have revealed genetic and phenotypic …
anaerobic, or a combination of both. … A number of studies have revealed genetic and phenotypic …