Bad to the bone: the effects of therapeutic glucocorticoids on osteoblasts and osteocytes
M Gado, U Baschant, LC Hofbauer… - Frontiers in …, 2022 - frontiersin.org
… doses of glucocorticoids decreases bone mass … of glucocorticoid receptors across all skeletal
cell populations and their respective progenitors, therapeutic glucocorticoids affect skeletal …
cell populations and their respective progenitors, therapeutic glucocorticoids affect skeletal …
The impact of high dose glucocorticoids on bone health and fracture risk in systemic vasculitides
CD Box, O Cronin, B Hauser - Frontiers in Endocrinology, 2022 - frontiersin.org
… glucocorticoid or combination treatments. This review will outline the known mechanism of
bone loss … Osteoporosis treatment with specific consideration for patients with vasculitis will be …
bone loss … Osteoporosis treatment with specific consideration for patients with vasculitis will be …
Endogenous glucocorticoid metabolism in bone: friend or foe
CS Martin, MS Cooper, RS Hardy - Frontiers in Endocrinology, 2021 - frontiersin.org
… corticosteroids are able to enter bone cells. Here 11β-HSD1 can further activate and amplify
the actions of corticosteroids … bone metabolism in osteoclasts, osteocytes and osteoblasts. …
the actions of corticosteroids … bone metabolism in osteoclasts, osteocytes and osteoblasts. …
The role of glucocorticoids in inflammatory diseases
SD Reichardt, A Amouret, C Muzzi, S Vettorazzi… - Cells, 2021 - mdpi.com
… For more than 70 years, glucocorticoids (GCs) have been a powerful and affordable
treatment option for inflammatory diseases. However, their benefits do not come without a cost, …
treatment option for inflammatory diseases. However, their benefits do not come without a cost, …
Distinct glucocorticoid receptor actions in bone homeostasis and bone diseases
S Lee, BT Krüger, A Ignatius… - Frontiers in …, 2022 - frontiersin.org
… itself hamper bone integrity. GC signaling is also important for fracture healing and rheumatoid
… This review summarizes the complexity of GC actions via GR in bone cells at cellular and …
… This review summarizes the complexity of GC actions via GR in bone cells at cellular and …
The effect of acknowledged and novel anti-rheumatic therapies on periodontal tissues—a narrative review
MA Martu, GA Maftei, I Luchian, OM Stefanescu… - Pharmaceuticals, 2021 - mdpi.com
… has been demonstrated to diminish rheumatic disease … corticosteroids on a group of
patients with chronic obstructive pulmonary disease concluded that this therapy may affect bone …
patients with chronic obstructive pulmonary disease concluded that this therapy may affect bone …
Steroids in Lupus: Enemies or Allies
E Enríquez-Merayo, MJ Cuadrado - Journal of Clinical Medicine, 2023 - mdpi.com
… Glucocorticoids are the gold standard treatment for reducing immune activation and
inflammation in a wide range of inflammatory and systemic autoimmune diseases. Glucocorticoids …
inflammation in a wide range of inflammatory and systemic autoimmune diseases. Glucocorticoids …
[HTML][HTML] An overview of glucocorticoid-induced osteoporosis
I Ilias, C Milionis, E Zoumakis - Endotext [Internet], 2022 - ncbi.nlm.nih.gov
… risk have been presented that take into account glucocorticoid dosage for the Fracture Risk
… GCs are administered; bone loss is more rapid in the first months of therapy. Patients on GCs …
… GCs are administered; bone loss is more rapid in the first months of therapy. Patients on GCs …
When to start and stop bone-protecting medication for preventing glucocorticoid-induced osteoporosis
… % of US patients with chronic conditions warranting glucocorticoid exposure received any
… studies of glucocorticoid effects on bone cell function have been recently published (39, 43). …
… studies of glucocorticoid effects on bone cell function have been recently published (39, 43). …
Endocrine Disorders in Autoimmune Rheumatological Diseases: A Focus on Thyroid Autoimmune Diseases and on the Effects of Chronic Glucocorticoid Treatment
F Egalini, M Parasiliti Caprino, G Gaggero, V Cappiello… - Endocrines, 2021 - mdpi.com
… Moreover, as glucocorticoids still represent a leading treatment for systemic … rheumatological
diseases, our secondary aim is to summarize the main effects of glucocorticoids treatment …
diseases, our secondary aim is to summarize the main effects of glucocorticoids treatment …