… AMPK; so it is unable to phosphorylate TET2 and TSC1/2 … Hyperglycemia linked diabetes
to cancer via the glucose-AMPK-TET2-… If we alter the biosynthesis of AMPK and TET2 natural …

… the genesis of cancer could be due to the unstable form of the AMPK-TET2 axis under …
Glucoseregulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer…

… AMPK- TET2- 5hmC axis signaling pathway, linking the level of extracellular glucose to the
dynamic epigenetic regulation of 5hmC with implications in diabetes and cancer (… reveal that …

… A western blot analysis revealed that in both the CRC cell … AMPK modulates TET2 stability
through phosphorylation of … AMPK, has a TET2-dependent anti-tumor effect in diabetic nude …

… cancer genes compared with controls (3). The meta-study also revealed that genes encoding
2 epigenetic regulators, TET2 … of the TET2 protein via the AMPK signaling pathway (13). …

… TET2 is an important link between diabetes and cancer… Glucose-regulated phosphorylation
of TET2 by AMPK reveals a pathway linking diabetes to cancer (13). Metformin is a first-line …

… Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes
to cancer. … We next tested the ability of AMPK to phosphorylate TET2 in vitro. Recombinant …

… multivariate analysis revealed that the AMPK high/TET2 low … expression levels of AMPK or
phosphorylated AMPK have been … of AMPK/TET2 expression levels in diabetes mellitus based …

… revealed a positive association between SIRT6 and TET2 activity (… pathway, the
glucose-AMPK-TET2-5hmC axis, which links the … function of TET2, increasing the risk of cancer. …

… diabetes-induced neuronal apoptosis by regulating TET2 function through improving
phosphorylate AMPK … of DP on TET2, we determined the protein level of AMPK and p-AMPK in the …