Growth hormone, insulin-like growth factors, and IGF binding proteins

CJ Rosen, S Yakar - Principles of bone biology, 2020 - Elsevier
stimulation of bone formation, recruitment of osteoblasts and … GH secretion in male and
female rats is identical after birth … a putative IGFBP-3 receptor has not been cloned, IGFBP-3 has …

The actions of IGF-1 in the growth plate and its role in postnatal bone elongation

HL Racine, MA Serrat - Current osteoporosis reports, 2020 - Springer
… role in the transformation of chondrocytes to osteoblasts [16••]. … growth include growth
hormone (GH), insulin-like growth … IGF binding protein-3 (IGFBP-3) is the major carrier of IGF-1 in …

The role of insulin-like growth factor-1 in bone remodeling: A review

J Fang, X Zhang, X Chen, Z Wang, S Zheng… - International Journal of …, 2023 - Elsevier
… IGF-1, a major tissue development growth hormone, is expressed … IGFBP-3 signaling pathway
has a decisive effect on the … that PTH stimulates the production of IGF-1 in osteoblasts, and …

Effects of GH/IGF axis on bone and cartilage

M Dixit, SB Poudel, S Yakar - Molecular and cellular endocrinology, 2021 - Elsevier
… The anabolic growth hormone (GH)/Insulin like growth factor-… -1 delivery system with reduced
IGFBP-3 and the ALS proteins, … ’ commitment to becoming osteoblasts or chondrocytes are …

Spirulina enhances bone modeling in growing male rats by regulating growth-related hormones

JA Cho, SY Baek, SH Cheong, MR Kim - Nutrients, 2020 - mdpi.com
hormone and growth hormone activities, as well its increased … stimulates the proliferation
and differentiation of osteoblast … Therefore, in this study, we examined the IGFBP-3 level in …

Microgravity, bone homeostasis, and insulin-like growth factor-1

JK Smith - Applied Sciences, 2020 - mdpi.com
… newly liberated growth factors stimulate osteoblasts to evolve … growth is controlled by growth
hormone which stimulates … specific binding protein, IGFBP-3 stimulated bone turnover in an …

The effect of Nigella sativa on serum levels of insulin-like growth factor and its binding proteins in postmenopausal women with low bone density: A triple-blind …

S Abdolalipour, AM Iranshahi, M Amirpour… - Indian Journal of …, 2023 - op.niscpr.res.in
… Impaired growth hormone (GH) or insulin-like growth factor-1 (IGF… of bone protein and
proliferation of osteoblasts in in- … In the present study, a significant increase in IGFBP-3 levels was …

[HTML][HTML] Insulin-like growth factor binding protein-5 in physiology and disease

C Duan, JB Allard - Frontiers in endocrinology, 2020 - frontiersin.org
IGFBP-3 levels and a 60% increase in total IGF levels (45). The deletion of PAPP-A2 in
osteoblast … About 75–80% of circulating IGF is found in a ternary complex with IGFBP-3 or−5 (9). …

IGF axis expression and activity in differentiating dental pulp cells

HAM Al-Khafaji - 2020 - etheses.whiterose.ac.uk
growth factor acts in concert with pituitary growth hormone to … in ALP activity in cultures of
rat tibial osteoblasts [102], and … , IGF action on osteoblasts is enhanced by IGFBP-3 [111]. A …

[HTML][HTML] Recombinant human insulin-like growth factor-1 promotes osteoclast formation and accelerates orthodontic tooth movement in rats

JX Peng, XY Guan, GH Li, JL Zhong… - Journal of Applied Oral …, 2021 - SciELO Brasil
… that recombinant human growth hormone could stimulate IGF-1 … -like growth factor (IGF)
binding protein-3 (IGFBP-3) on … expressed on the surface of osteoblasts by binding to osteoclast …