… expressed in osteoclasts and osteoblasts and are considered essential in maintaining bone
homeostasis by regulating the functions of both osteoclasts and osteoblasts. Additionally, …

… of IGFBP-3, -4, and -5 in osteoblasts (122, 123). IGFBP-5 … In rats, GCs reduce the action of
follicle-stimulating hormone (… GH response to growth hormone–releasing hormone (GHRH) …

… The authors further observed in a UAC rat model that autophagy … et al. reported that highly
expressed IGFBP-3 and -5 … These authors confirmed that iPTH increased the osteoblastic …

… thus stimulating an antioxidant response in osteoblasts subjected … parathyroid hormone (PTH),
calcitonin, growth hormone, and … IGF-binding protein 3 (IGFBP-3), which regulate cartilage …

… hormones from the growth hormone (GH)/IGF-I axis maintain slow, but continuous, bone
growth… However, if E acts directly on osteoblasts to stimulate bone formation, postmenopausal E …

… form the skeleton called osteoblasts contrasts with their extra … As circulating IGF- 1 is regulated
by growth hormone (GH),64 … bioavailability in rats. J Nutr Biochem. 2011;22(4):318- 327. …

… additional osteoblasts and osteoclasts into the growth plate … of growth hormone (GH),
luteinizing hormone (LH)/follicle-… to insulin-like growth factor-binding protein 3 (IGFBP-3), a …

… to baseline levels, whereas IGFBP-3 was markedly increased … , hinder the anabolic effects
of growth hormone, and suppress IGF-… Leptin has also been shown to promote osteoblast …

… a reduced number of osteoblasts in the inner layer of the perichondrium and the proliferating
zone of the growth plate, which indicates a role of IGF-IR in osteoblast proliferation and …

… (growth hormone)—IGF-1 (insulin-like growth factor 1) axis. Significantly, the concentrations
of IGF-1 and insulin-like growth factor binding protein-3 (IGFBP-3… , osteoblast apoptosis, and …