Antimicrobial Effect of Extracellular Vesicles Derived From Human Oral Mucosal Epithelial Cells on Candida albicans

M Zhao, M Zhang, K Xu, K Wu, R Xie, R Li… - Frontiers in …, 2022 - frontiersin.org
… Both immune cells and nonimmune cells can produce EVs, which … growth or promote
disease development (7–10). EVs derived from oral mucosal epithelial cells can inhibit the growth

… human interleukin 17A enhances the anti‐Candida effect of human oral mucosal epithelial cells by inhibiting Candida albicans growth and inducing antimicrobial …

L Jiang, M Fang, R Tao, X Yong… - Journal of Oral Pathology …, 2020 - Wiley Online Library
human interleukin 17A may inhibit C … a human oral mucosa epithelial cell model of C albicans
infection. C albicans is the most common and virulent Candida species that causes human

IL-1α released from oral epithelial cells upon candidalysin exposure initiates an early innate epithelial response

M Hanaoka, E Domae - International Immunology, 2021 - academic.oup.com
… We found that human oral epithelial cells released IL-1α rapidly … Oral candidiasis is an
opportunistic infection of the oral cavity of … Simultaneous inhibition of IL-1α and EGFR abrogates …

Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors

M Swidergall, NV Solis, N Millet, MY Huang… - PLoS …, 2021 - journals.plos.org
… Previously, we determined that treating oral epithelial cells with interferon-γ or an inhibitor of
the … The OKF6/TERT-2 immortalized human oral epithelial cell line was kindly provided by J. …

Oral Epithelial Cells Distinguish between Candida Species with High or Low Pathogenic Potential through MicroRNA Regulation

M Horváth, G Nagy, N Zsindely, L Bodai, P Horváth… - Msystems, 2021 - Am Soc Microbiol
… Our study reveals that the distinct nature of human oral epithelial cell responses toward C. …
oxygen radicals) that inhibit or kill diverse microbes (1). Epithelial cells also actively contribute …

[HTML][HTML] … and cell cycle gene expression in normal and neoplastic oral epithelial cells stimulated with soluble factors from single and dual biofilms of Candida albicans …

MI Amaya Arbelaez, ACA de Paula e Silva… - Frontiers in Cellular …, 2021 - frontiersin.org
… Thus, failures in cell cycle inhibitors and excessive signaling of positive regulators of … -oncogenes,
the cell cycle profile, and cell viability in the oral epithelial cells (normal and neoplastic…

Oral Cavity and Candida albicans: Colonisation to the Development of Infection

M Patel - Pathogens, 2022 - mdpi.com
… The human oral cavity is a unique site, which becomes colonised with … in the inhibition of the
establishment of Candida [44]. … In oral epithelial cells, candidalysin causes cell damage and …

Candidalysin is a potent trigger of alarmin and antimicrobial peptide release in epithelial cells

J Ho, DN Wickramasinghe, SA Nikou, B Hube… - Cells, 2020 - mdpi.com
… ) inhibitors was used to lyse cells following experimentation. … ] are produced by both Candida
and epithelial cells, we used … and AMPs from human oral epithelial cells, and highlights the …

Candida albicans Enhances the Progression of Oral Squamous Cell Carcinoma In Vitro and In Vivo

M Vadovics, J Ho, N Igaz, R Alföldi, D Rakk, É Veres… - MBio, 2022 - Am Soc Microbiol
… The human oral epithelial cell line OKF6/TERT2 was kindly provided by J. Rheinwald (Harvard
University, Cambridge, Massachusetts). We also thank Olivia Hepworth, Nicole Ponde, …

Potential role of Candida albicans secreted aspartic protease 9 in serum induced-hyphal formation and interaction with oral epithelial cells

H Yang, PCS Tsang, EHN Pow, OLT Lam… - Microbial …, 2020 - Elsevier
… -inducing stimuli via a cAMP-protein kinase A pathway mediated by EFG1, and contributes
to the process of invasion of Candida into the epithelial cells, leading to host cell damage. …