… ) causes an array of pathologies, the most aggressive of which is adult T-cell leukemia (ATL),
a … and on the interplay between these two viral proteins (Tax and HBZ) with the host innate …

… adult T cell leukemia/lymphoma (ATL) decades after infection… the mechanisms of action of
Tax and HBZ with the comprehensive … activities of Tax and Rex, HTLV-1 structural proteins are …

… ) and helix basic zipper protein (HBZ), which are considered … HTLV-1 are largely attributed
to the effects of the Tax protein. … alterations that result in adult T-cell leukemia lymphoma. …

… ) is the etiological agent of adult T-cell leukemia/lymphoma (… The HTLV-1 trans-activator
protein Tax is expressed from a … In addition to Tax, HBZ is a key viral factor important for HTLV-1 …

… is the causative agent of a spectrum of diseases including the aggressive adult T-cell … -HTLV-1-targeted
therapies of ATL with a special focus on two viral proteins, Tax and HBZ, …

… While Tax-1 can be found in both the cytoplasm and nucleus of … of HTLV-1 HBZ protein
during adult T-cell leukemia-lymphoma progression. Primary infection of T cells by HTLV-1 is …

… of HBZ on Tax-induced transformation and cellular effects. This study helps understanding
long-term HTLV-1 … Adult T-cell Leukemia/Lymphoma (ATL) is an aggressive hematological …

… The human T cell leukemia/lymphoma virus-type 1 (HTLV-1), … lymphoid lineage designated
Adult T cell leukemia (ATL) (2). … Tax-1 and HBZ are considered the two crucial factors for the …

… , such as adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-… TAX and HBZ are crucial for
maintaining HTLV-1 infection by … of HBZ mRNA and HBZ proteins, we introduce HBZ as an …

… Adult T-cell leukemia/lymphoma (ATLL) is a type of … proteins, including Basic Zipper Factor
(HBZ), p13II/p8, p30II, p12I, … The HTLV-1 Tax protein affects EZH2, leading to H3K27 me3 …