Interplay between innate immunity and the viral oncoproteins Tax and HBZ in the pathogenesis and therapeutic response of HTLV-1 associated adult T cell leukemia
H El Hajj, A Bazarbachi - Frontiers in Immunology, 2022 - frontiersin.org
… ) causes an array of pathologies, the most aggressive of which is adult T-cell leukemia (ATL),
a … and on the interplay between these two viral proteins (Tax and HBZ) with the host innate …
a … and on the interplay between these two viral proteins (Tax and HBZ) with the host innate …
HTLV-1 replication and adult T cell leukemia development
CZ Giam - Viruses and Human Cancer: From Basic Science to …, 2021 - Springer
… adult T cell leukemia/lymphoma (ATL) decades after infection… the mechanisms of action of
Tax and HBZ with the comprehensive … activities of Tax and Rex, HTLV-1 structural proteins are …
Tax and HBZ with the comprehensive … activities of Tax and Rex, HTLV-1 structural proteins are …
Molecular biology of human T cell leukemia virus
L Ratner - Seminars in diagnostic pathology, 2020 - Elsevier
… ) and helix basic zipper protein (HBZ), which are considered … HTLV-1 are largely attributed
to the effects of the Tax protein. … alterations that result in adult T-cell leukemia lymphoma. …
to the effects of the Tax protein. … alterations that result in adult T-cell leukemia lymphoma. …
Mechanisms of oncogenesis by HTLV-1 Tax
… ) is the etiological agent of adult T-cell leukemia/lymphoma (… The HTLV-1 trans-activator
protein Tax is expressed from a … In addition to Tax, HBZ is a key viral factor important for HTLV-1 …
protein Tax is expressed from a … In addition to Tax, HBZ is a key viral factor important for HTLV-1 …
Adult T-cell leukemia: a comprehensive overview on current and promising treatment modalities
R Hleihel, A Akkouche, H Skayneh, O Hermine… - Current Oncology …, 2021 - Springer
… is the causative agent of a spectrum of diseases including the aggressive adult T-cell … -HTLV-1-targeted
therapies of ATL with a special focus on two viral proteins, Tax and HBZ, …
therapies of ATL with a special focus on two viral proteins, Tax and HBZ, …
[HTML][HTML] Dual cytoplasmic and nuclear localization of HTLV-1-encoded HBZ protein is a unique feature of adult T-cell leukemia
G Forlani, M Shallak, A Tedeschi, I Cavallari… - …, 2021 - ncbi.nlm.nih.gov
… While Tax-1 can be found in both the cytoplasm and nucleus of … of HTLV-1 HBZ protein
during adult T-cell leukemia-lymphoma progression. Primary infection of T cells by HTLV-1 is …
during adult T-cell leukemia-lymphoma progression. Primary infection of T cells by HTLV-1 is …
In vivo antagonistic role of the Human T-Cell Leukemia Virus Type 1 regulatory proteins Tax and HBZ
A Akkouche, S Moodad, R Hleihel, H Skayneh… - PLoS …, 2021 - journals.plos.org
… of HBZ on Tax-induced transformation and cellular effects. This study helps understanding
long-term HTLV-1 … Adult T-cell Leukemia/Lymphoma (ATL) is an aggressive hematological …
long-term HTLV-1 … Adult T-cell Leukemia/Lymphoma (ATL) is an aggressive hematological …
The Road to HTLV-1-Induced Leukemia by Following the Subcellular Localization of HTLV-1-Encoded HBZ Protein
RS Accolla - Frontiers in Immunology, 2022 - frontiersin.org
… The human T cell leukemia/lymphoma virus-type 1 (HTLV-1), … lymphoid lineage designated
Adult T cell leukemia (ATL) (2). … Tax-1 and HBZ are considered the two crucial factors for the …
Adult T cell leukemia (ATL) (2). … Tax-1 and HBZ are considered the two crucial factors for the …
Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)
S Ahmadi Ghezeldasht, DJ Blackbourn… - Critical Reviews in …, 2023 - Taylor & Francis
… , such as adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-… TAX and HBZ are crucial for
maintaining HTLV-1 infection by … of HBZ mRNA and HBZ proteins, we introduce HBZ as an …
maintaining HTLV-1 infection by … of HBZ mRNA and HBZ proteins, we introduce HBZ as an …
Therapeutic approaches for HTLV-1-associated adult T-cell leukemia/lymphoma: a comprehensive review
A Letafati, R Soheili, M Norouzi, P Soleimani… - Medical Oncology, 2023 - Springer
… Adult T-cell leukemia/lymphoma (ATLL) is a type of … proteins, including Basic Zipper Factor
(HBZ), p13II/p8, p30II, p12I, … The HTLV-1 Tax protein affects EZH2, leading to H3K27 me3 …
(HBZ), p13II/p8, p30II, p12I, … The HTLV-1 Tax protein affects EZH2, leading to H3K27 me3 …