HNRNPC downregulation inhibits IL‐6/STAT3‐mediated HCC metastasis by decreasing HIF1A expression

D Liu, X Luo, M Xie, T Zhang, X Chen, B Zhang… - Cancer …, 2022 - Wiley Online Library
… between hepatocellular carcinoma (HCC) and normal liver … The examinations of serum
alpha-fetoprotein (AFP) level and … The half-life of HIF1A mRNA was markedly decreased in the …

Advances in the treatment of intrahepatic cholangiocarcinoma: An overview of the current and future therapeutic landscape for clinicians

D Moris, M Palta, C Kim, PJ Allen… - CA: a cancer journal …, 2023 - Wiley Online Library
… ICC, whereas elevated alpha-fetoprotein levels suggest HCC … of major hepatic resection;
downstaging of the primary tumor … Because of the short half-life and high first-pass metabolism …

CMTM6 promotes hepatocellular carcinoma progression through stabilizing β-catenin

Q Liu, J Wang, Z Guo, H Zhang, Y Zhou, P Wang, T Li… - Cancer Letters, 2024 - Elsevier
alpha-fetoprotein (AFP) levels, supporting its potential as a … target and prognostic indicator
across various cancers. … degradation rate was significantly slowed down, and the half-life of β-…

Circulating Biomarkers for Early Diagnosis of Hepatocellular Carcinoma

H Van Tong, P Van Dung, NTM Diep… - Hepatocell. Carcinoma …, 2022 - books.google.com
Alpha-fetoprotein (AFP) is a large serum glycoprotein that is … can be used as a prognosis
indicator for HCC. Its expression … as a predictor of recurrence after liver resection. However, the …

Unleashing the potential of gene signatures as prognostic and predictive tools: A step closer to personalized medicine in hepatocellular carcinoma (HCC)

A Pourbagheri‐Sigaroodi, F Fallah… - Cell Biochemistry …, 2024 - Wiley Online Library
… 8, 9 as liver transplantation and hepatic resection have emerged as the … studied prognostic
biomarkers in HCC is alpha-fetoprotein (… Due to the short half-life of ctDNA, it can be used for …

The current status and future prospects for conversion therapy in the treatment of hepatocellular carcinoma

J Bai, M Huang, B Song, W Luo… - Technology in Cancer …, 2023 - journals.sagepub.com
… for surgery who had a 1-year recurrence-free survival rate of … to the half-life of the drug for
patients with convertible resection. … serum alpha-fetoprotein (AFP) levels or activity per tumor

[HTML][HTML] Circulating tumor DNA correlates with microvascular invasion and predicts tumor recurrence of hepatocellular carcinoma

J Wang, A Huang, YP Wang, Y Yin, PY Fu… - Annals of …, 2020 - ncbi.nlm.nih.gov
… It is reported that the half-life time of ctDNA in circulation was no more than 2 hours (44); …
days after surgery were all from tumor cells still remaining in the liver, either as early intrahepatic …

[HTML][HTML] The Significance of circulating tumor cells in patients with hepatocellular carcinoma: real-time monitoring and moving targets for cancer therapy

F Chen, Z Zhong, HY Tan, N Wang, Y Feng - Cancers, 2020 - mdpi.com
… Their half-life was estimated to be short, ranging from 1 to 2.4 h [73]. Approximately one …
with a lower ApoA-1 level had higher recurrence rate and shorter survival time [108]. Moreover, …

[PDF][PDF] Clinical significance of plasma free DNA concentration and integrity in detection of primary hepatocellular carcinoma

Y Zhen, W Qingbo, S Mu, S Bo - Revista Argentina …, 2020 - revistaclinicapsicologica.com
… of traditional tumor markers such as alpha-Fetoprotein (AFP), … CfDNA has a short half-life,
usually only 16 minutes, and can … , GPC-3, CK19 and CD31 as prognostic indicators, but these …

A novel strategy for the diagnosis, prognosis, treatment, and chemoresistance of hepatocellular carcinoma: DNA methylation

A Liu, Q Wu, D Peng, I Ares, A Anadón… - Medicinal Research …, 2020 - Wiley Online Library
… differentiated tumors, tumor recurrence after resection Being … serum alpha fetoprotein (AFP)
is the most widely used serum … has a longer elimination half-life and more extended exposure…