A review on microvascular hemodynamics: the control of blood flow distribution and tissue oxygenation

CJ Munoz, A Lucas, AT Williams… - Critical care …, 2020 - criticalcare.theclinics.com
… the capillary network. The capillary network then converges back into progressively larger
… Velocity profiles of human blood at normal and reduced hematocrit in glass tubes up to 130 …

Abnormal morphology biases hematocrit distribution in tumor vasculature and contributes to heterogeneity in tissue oxygenation

MO Bernabeu, J Köry, JA Grogan… - Proceedings of the …, 2020 - National Acad Sciences
… and PS in a tumor-inspired 3D microvascular network. Our intention was to understand the
extent to … S6 show that for larger values of λ , the differences in the oxygen distribution in the …

Tissue Oxygenation Around Capillaries: Effects of Hematocrit and Arteriole Oxygen Condition

FA Amiri, J Zhang - Bulletin of Mathematical Biology, 2023 - Springer
… better understanding of oxygen transport in microcirculation. … actual microcirculation, it allows
us to focus on major factors … much more complicated in microvascular networks (Cassot et al…

Analysis and prediction of hematocrit in microvascular networks

G Li, T Ye, Z Xia, S Wang, Z Zhu - International Journal of Engineering …, 2023 - Elsevier
oxygen. The present work aims to analyze and predict the hematocrit distribution in microvascular
networks … , and it varies steadily over time in wide vessels but periodically fluctuates in …

Temporal-spatial heterogeneity of hematocrit in microvascular networks

G Li, T Ye, B Yang, S Wang, X Li - Physics of Fluids, 2023 - pubs.aip.org
major feature in microvascular networks is … oxygen heterogeneity in tumor tissue. They
reported that the tumor vasculature can bias the hematocrit distribution in tumor vascular networks

Simulation of oxygen transport and estimation of tissue perfusion in extensive microvascular networks: Application to cerebral cortex

JT Celaya-Alcala, GV Lee, AF Smith… - Journal of Cerebral …, 2021 - journals.sagepub.com
… flow directions in large parts of the network. Such specification … In reality, hematocrit varies
in microvascular networks as a … tissue oxygenation by extensive microvascular networks with …

Blood flow, capillary transit times, and tissue oxygenation: the centennial of capillary recruitment

L Østergaard - Journal of Applied Physiology, 2020 - journals.physiology.org
… (CTH) and capillary hematocrit (HCT) across open capillaries … B: the corresponding relation
for a tissue volume with a large … Simulations of blood flow through microvascular networks

Effect of vessel compression on blood flow in microvascular networks and its implications for tumour tissue hypoxia

R Enjalbert, T Krüger, MO Bernabeu - Communications Physics, 2024 - nature.com
… , leading to increased tissue oxygen at a network level 13 . We … distribution of RBCs, and
therefore haematocrit, at a network … over a wide range of inlet haematocrits to the network, from …

Red blood cell lingering modulates hematocrit distribution in the microcirculation

Y Rashidi, G Simionato, Q Zhou, T John, A Kihm… - Biophysical …, 2023 - cell.com
… the oxygen delivery and solute transport to tissues. This process relies on the partitioning of
RBCs at successive bifurcations throughout the microvascular network, … usually exhibit large

Functional implications of microvascular heterogeneity for oxygen uptake and utilization

TK Roy, TW Secomb - Physiological Reports, 2022 - Wiley Online Library
… in blood flow and hematocrit. Mechanisms have evolved to … Microvascular networks must
therefore combine hierarchical … to the heterogeneity of tissue oxygen levels. Arrow with blunt …