Interaction between Nuclear Receptor and Alpha‐Adrenergic Agonist Subtypes in Metabolism and Systemic Hemodynamics of Spontaneously Hypertensive Rats

S Afzal, MA Sattar, I Albokhadaim, A Attiq… - PPAR …, 2024 - Wiley Online Library
hypertension and heart failure [11] is the selective angiotensin-II AT1 receptor blocker
irbesartan. … Biochemical analysis of the plasma and urine samples necessitated freezing them at -…

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker on oxidative stress and metabolism of elements in kidney of STZ-induced diabetic …

NP Özsobacı, M Karataş, M Tunçdemir… - Archives of Biochemistry …, 2024 - Elsevier
… of irbesartan, an AT1 receptor antagonist, because other studies [17,50] have shown that
this dose reduces systemic blood pressure, regulates renal haemodynamicblood pressure, …

Mechanism of action of drugs used in hypertension

RH Mazumdar, AMAM Bhowmik… - How Synthetic Drugs …, 2022 - books.google.com
biological effects are observed by AngII on angiotensin I (AT1… 108109 Benazepril exerts
hemodynamic effects that … Irbesartan selectively binds with AT1 receptor and inhibits AngII …

A comparative study between angiotensin receptor neprilysin inhibitor (thiorphan/irbesartan) with each of nitrate and carvedilol in a rat model of myocardial ischemic …

T Mohammed Abdulsalam, AH Hasanin… - Fundamental & …, 2023 - Wiley Online Library
… cardiac damage, preserving the cardiac hemodynamic functions. Furthermore, Wang and
his … cardioprotective effects compared with AT1 receptor blockade alone in hypertensive rats. …

[PDF][PDF] Clinical effect of Perindopril or irbesartan combined with diltiazem moderate primary hypertension outpatients

Y Chang, Y Ding - core.ac.uk
hemodynamics, blood pressure is considered to be the leading factor of LV remodeling and
hypertrophy, and changes in blood pressure … of the biochemical laboratory of our university. …

The role of angiotensin II type 1 receptor pathway in cerebral ischemia‒reperfusion injury: Implications for the neuroprotective effect of ARBs

S Huang, M Zhang - Neuroprotection, 2024 - Wiley Online Library
… to a biochemical cascade that causes deteriorative effects in … altered shear force and
hemodynamic changes in endothelial … An I/R model in Ang II‐induced hypertensive rats revealed …

Angiotensin receptor–neprilysin inhibitor (thiorphan/irbesartan) improved cardiac function in a rat model of myocardial ischemic reperfusion injury

T Mohammed Abdulsalam, AH Hasanin… - Fundamental & …, 2023 - Wiley Online Library
… for all the biochemical and immunohistochemistry studies. … hypertensive rats, but in the
present study, TH/IRB combination therapy was used in normotensives rats so hypotensive effect

Pharmacology of Angiotensin and Its Receptors

S Biswal, R Ghosh, PC Acharya - Frontiers in Pharmacology of …, 2020 - Springer
… Patients having poor control over blood pressure are usually … for treating hypertension;
however, irbesartan and candesartan … effects, although they both share the same biochemical

[HTML][HTML] Current and emerging classes of pharmacological agents for the management of hypertension

U Ojha, S Ruddaraju, N Sabapathy… - American Journal of …, 2022 - Springer
… NO in the cardiovascular system, eliciting many of the biological actions of NO via cGMP [82].
The … given the metabolic and hemodynamic abnormalities present in this group. Causes of …

[HTML][HTML] Role of the central renin‑angiotensin system in hypertension

C Su, J Xue, C Ye, A Chen - … journal of molecular …, 2021 - spandidos-publications.com
… into the MnPO of rats selectively increased the hemodynamic … AT-1R blocker, irbesartan,
effectively attenuated the effect of … The expression level of AT-1R determines the biological