Temporal and epigenetic control of plasticity and fate decision during CD8+ T-cell memory differentiation
L Pace - Cold Spring Harbor Perspectives in Biology, 2021 - cshperspectives.cshlp.org
… in the field of memory CD8 + T-cell differentiation, and we will … basis of CD8 + T lymphocyte
heterogeneity, the timing of cell fate decisions, and the epigenetic networks controlling T-cell …
heterogeneity, the timing of cell fate decisions, and the epigenetic networks controlling T-cell …
Divide and Conquer: Phenotypic and Temporal Heterogeneity Within CD8+ T Cell Responses
AC Richard - Frontiers in Immunology, 2022 - frontiersin.org
… highlights how heterogeneity of T cell responses can propagate from variation in expression
of a single chemokine receptor or subtle cell positioning all the way to differentiation fate. …
of a single chemokine receptor or subtle cell positioning all the way to differentiation fate. …
Memory T-cell heterogeneity and terminology
Y Muroyama, EJ Wherry - Cold Spring Harbor …, 2021 - cshperspectives.cshlp.org
… ), has the potential to differentiate into long-lived memory CD8 T (Tmem) cells. Some SLECs
… suggested to regulate early Teff cell differentiation and Teff versus Tmem cell fate decisions. …
… suggested to regulate early Teff cell differentiation and Teff versus Tmem cell fate decisions. …
Epigenetics and CD8+ T cell memory*
G Montacchiesi, L Pace - Immunological Reviews, 2022 - Wiley Online Library
… commitment of effector vs memory CD8 + T cell subsets have … Although the mechanisms of
CD8 + T cell fate decision have … the heterogeneity of numerous constellation of T cell subsets, …
CD8 + T cell fate decision have … the heterogeneity of numerous constellation of T cell subsets, …
Motility matters: How CD8+ T-cell trafficking influences effector and memory cell differentiation
Y Farsakoglu, B McDonald… - Cold Spring Harbor …, 2021 - cshperspectives.cshlp.org
… regulation of effector and memory CD8 + T-cell fate determination, … , activated CD8 + T cells
form a heterogeneous effector … CD8 + T cells acquire a terminally differentiated effector state …
form a heterogeneous effector … CD8 + T cells acquire a terminally differentiated effector state …
A single-cell perspective on memory T-cell differentiation
L Kretschmer, DH Busch… - Cold Spring Harbor …, 2021 - cshperspectives.cshlp.org
… Stem-cell-like features of central memory CD8 T cells. (A) A single naive precursor … As
we have highlighted in this review, single T-cell fate mapping in vivo has provided us with rich …
we have highlighted in this review, single T-cell fate mapping in vivo has provided us with rich …
Transcriptional Control of Cell Fate Determination in Antigen-Experienced CD8 T Cells
S Tsuda, ME Pipkin - Cold Spring Harbor perspectives in …, 2022 - cshperspectives.cshlp.org
… phase exhibit substantial phenotypic heterogeneity, which correlates with different potentials
for terminal differentiation or developing into specific memory CD8 T-cell subclasses during …
for terminal differentiation or developing into specific memory CD8 T-cell subclasses during …
Quantitating CD8+ T cell memory development
T Nizharadze, NB Becker, T Höfer - Trends in Immunology, 2023 - cell.com
… central memory CD8 + T cell precursors proliferate more slowly than terminally differentiating
effector CD8 + T cell… T cell fate, including memory development, has not been continuously …
effector CD8 + T cell… T cell fate, including memory development, has not been continuously …
Epigenetics of T cell fate decision
L Pace, S Amigorena - Current Opinion in Immunology, 2020 - Elsevier
… Inter-clonal and intra-clonal functional heterogeneity of effector and memory CD4 + T cell
subsets have also been described in response to viral, bacterial and fungal antigens [3]. …
subsets have also been described in response to viral, bacterial and fungal antigens [3]. …
Delayed Differentiation Makes Many Models Compatible with Data for CD8+ T Cell Differentiation
… either die or form memory CD8 + T cells during the contraction … the heterogeneity in marker
distributions for different naïve CD8 + T cell families, they showed that a linear differentiation …
distributions for different naïve CD8 + T cell families, they showed that a linear differentiation …