… avidity of vaccine-induced antigen-specific CD8 T-cells from melanoma patients after multiple
monthly vaccine injections. We found that high … selection of CD8-independent TCRs over …

… Tetramers bearing a mutation in the CD8 binding site selectively bind to higher avidity T cells,
but bind not to low avidity … avidity or may not even identify important antigen-specific TCR …

… avidity can drive the clonal evolution of virus antigen-specific CD8 T cells, and how this process
is determined … showing the proportion of CD8-independent TCRαβ clonotypes, classified …

… the detailed role of affinity and avidity in shaping the quality of … -week-old mice were identified
using Tetrameric A2Kb/NY-ESO… transfer experiments indicate that antigen specific CD4 + T …

… a large amount of cancer antigen-specific effector T cells that … tetramer staining ( Figure
4c ). Using the CLDN6 132–140 peptide, we tested TCR avidity against the peptide and found …

… Using MR1-5-OP-RU tetramers, we determined the frequency … , all tetramers stained the
CD8αα cell line with a higher intensity … rate was higher, and overall avidity of MR1 tetramers was …

… infection elicits a strong antigen- specific CTL response. We … We found that intranasal or
intramuscular immunization with … 1- specific CTL responses were analysed by tetramer staining. …

… (38) have successfully identified antigen-specific T cells from … well as measured by pHLA
tetramer staining (Figure 7A). All … cell clones we identified varied in their functional avidity, with …

… In this study, we found that CTL expression of the NK … regulate TCR functional avidity of
human TAA-specific CTLs, allowing … CTLs were sorted by flow cytometry based on the staining of …

… FLU is highly efficient in inducing antigen specific CD8+T cell … of antigen-specific cytotoxic
T cells but also their avidity to … We found that intranasal or intramuscular immunization with …