… shown pH dependency of relaxivity measurements using pH-… shows the relaxivity determination
of Gd-BTDO3A at 3.0 T MRI. … In this study, a pHe-relaxivity calibration curve was obtained …

… an intratumoral pHe lower than the peritumoral pHe, with the … Representative MRI and
BIRDS data from a rat bearing an … One method to image pH is to measure the relaxivity of pH-…

… Shifts (BIRDS) which exploits the pH dependent chemical shifts of non-… Example of in vivo
imaging of U87 tumors in rat brain with … First, the transverse (r 2 ) relaxivity of the agent can be …

… Amine CEST provided pH-sensitivity through labeling the endogenous amine … pH-dependent
exchange rate. On the other hand, the reversible transverse relaxation rate quantified using …

… The average pHe measured in 4 rat gliomas from IEPA was … The APT imaging was used to
detect acidic pH in ischemic rat … This r1 relaxivity can then be used to estimate pHe by using …

… (r), related to their ability to generate contrast in MRI images. … 2+ ), have similar increases
in relaxivity for both longitudinal … for MRI Orthotopic C6 tumour model in male Wistar rats [64] …

… and phenylalanine phantom samples with pH ranging from … MTR asym from the influence of
tissue transverse relaxivity (T 2 … amine concentration on the pH dependency of CEST contrast…

… MR imaging relaxivity and in vitro MR imaging of CPP-2. (A) T 1 -weighted … (A) Representative
in vivo T 1 -weighted MR images of brains in intracranial C6 glioma-bearing rats before …

… Garcia-Martin ML, Martinez GV, Raghunand N, Sherry AD, Zhang S, Gillies RJ (2006) High
resolution pHe imaging of rat glioma using pH-dependent relaxivity. Magn Reson Med 55 (2): …

… to mapping pH in kidneys and rat brain glioma has been the … metal-center magnetic relaxivity
measured at 3.0 T for our pH-… pH quantification using this method of analysis is dependent …